DEVELOPMENT AND SUCCESSION OF TEETH IN PERAMELES. 517 
formig” tooth-germs of other writers. But the fact that 
such appearances occur intermittently throughout nearly 
the whole extent of the lengthy canine region seems sufficient 
to negative this idea. We can point to quite a number, no 
less than seven, absolutely separate and distinct “bud- 
hike enamel-germs” of this sort, existing in antero-pos- 
terior series by the side of the canine of this stage. Each of 
these is fairly bulky, pear-shaped, and concentrically encap- 
sulated. It is beyond doubt that they are nothing more than 
portions of the swollen free distal margin of the residual lamina 
which persists for some time after the antero-posterior con- 
tinuity of that margin has been interrupted by regressive pro- 
cesses. It is equally difficult to imagine a production of several 
rudimentary “ bud-like enamel-germs of replacing teeth” by 
the side of the single canine, or to imagine a primitively single 
“bud-like”’ germ subdivided at intervals into a lengthy longi- 
tudinal series of bud-like masses. 
Let it be specially noted that in the case before us we have 
presented the phenomenon of “knospenférmig” cell-masses, 
long persistent, and distinctly encapsulated by the surrounding 
connective tissue, i.e. offering the only credentials to which 
Leche appeals for the determination of such structures as true 
tooth-germs. The demonstration of their multiplicity in such 
a case as the present seems to us to be the reductio ad ab- 
surdum of the replacing-enamel-germ theory. 
It seems to us that the presence of these structures at a 
comparatively advanced stage of the canine tooth development 
is largely explicable by reason of the considerable bulk of the 
entire canine Anlage, to which attention has frequently been 
called in these pages. The notable size of the canine lamina 
is doubtless associated with a higher degree of formative 
activity, which is longer in being exhausted here than else- 
where. In any case we can attach no special morphological 
significance to the continued presence at this period of even 
such definite epithelial structures as those described. 
The two anterior premolars are large pointed teeth, and cause 
marked projection of the gum. Vestiges of the residual lamina 
