﻿158 
  H. 
  iM. 
  WOODCOCK. 
  

  

  is 
  possible. 
  Moreover 
  the 
  sporont 
  is 
  typically 
  extra-cellular 
  

   duriug 
  the 
  wliole 
  course 
  of 
  sporogony. 
  Compare 
  this 
  with 
  

   what 
  we 
  find 
  in 
  Klossiella. 
  In 
  Fig. 
  A 
  (1) 
  we 
  have 
  a 
  young 
  

   form 
  possessing, 
  at 
  most, 
  a 
  ver}^ 
  delicate 
  membrane, 
  and 
  lying 
  

   in 
  a 
  vacuole 
  in 
  a 
  host-cell 
  that 
  as 
  yet 
  shows 
  hardly 
  any 
  effects 
  

   of 
  the 
  parasitic 
  invasion. 
  Again, 
  this 
  young 
  '^sporont" 
  

   grows 
  from 
  10 
  ju 
  to 
  as 
  much 
  as 
  40 
  ju 
  ! 
  Further, 
  in 
  the 
  nuclei 
  

   and 
  nuclear 
  division 
  in 
  a 
  Coccidian 
  sporont 
  — 
  in 
  fact, 
  while 
  

   the 
  sporogonic 
  cycle 
  lasts 
  — 
  there 
  is 
  no 
  sign 
  of 
  karyosomes. 
  

   When, 
  as 
  in 
  C. 
  proprium, 
  these 
  are 
  retained 
  in 
  the 
  ripe 
  

   gametes 
  and 
  are 
  thus 
  present 
  in 
  the 
  oocyte, 
  they 
  are 
  in- 
  

   variably 
  left 
  behind 
  in 
  the 
  residual 
  cytoplasm 
  of 
  the 
  latter 
  

   and 
  take 
  no 
  part 
  in 
  spore-formation 
  ; 
  and 
  even 
  their 
  retention 
  

   up 
  to 
  this 
  stage 
  is 
  unusual. 
  The 
  presence 
  of 
  karyosomatic 
  

   nuclei 
  is, 
  in 
  short, 
  essentially 
  a 
  mark 
  of 
  schizogony, 
  be 
  it 
  

   male, 
  female, 
  or 
  indifferent 
  in 
  type; 
  and 
  it 
  is 
  a 
  feature 
  in 
  the 
  

   multiplicative 
  stages 
  before 
  us 
  (Fig. 
  A 
  2, 
  3, 
  4). 
  We 
  will 
  leave 
  

   out 
  of 
  account 
  the 
  markedly 
  peripheral 
  origin 
  of 
  the 
  "buds," 
  

   — 
  although 
  peripheral 
  budding 
  is 
  characteristic 
  of 
  endogenous 
  

   reproduction, 
  — 
  since 
  in 
  polyspoi'ous 
  types 
  (Klossia, 
  etc.) 
  

   there 
  is 
  a 
  tendency 
  to 
  a 
  similar 
  mode 
  of 
  origin 
  of 
  the 
  sporo- 
  

   blasts, 
  "with 
  the 
  formation 
  of 
  a 
  central 
  "reliquat 
  kystal." 
  

   Let 
  us 
  pass 
  on 
  to 
  the 
  "spores" 
  themselves. 
  There 
  is 
  now 
  no 
  

   doubt 
  about 
  the 
  occurrence 
  of 
  poly 
  zoic 
  spores; 
  Cyclospora 
  

   itself 
  and 
  the 
  re-investigated 
  Eucoccidium 
  ("Bene- 
  

   denia") 
  octopianum 
  are 
  instances 
  of 
  it, 
  — 
  so 
  it 
  is 
  quite 
  

   possible 
  that, 
  in 
  these 
  cases, 
  there 
  may 
  also 
  be 
  a 
  more 
  or 
  less 
  

   "barillet"-like 
  arrangement 
  of 
  tlie 
  sporozoites, 
  such 
  as 
  is 
  

   often 
  met 
  with 
  in 
  merozoites. 
  

  

  Here, 
  however, 
  the 
  resemblance 
  between 
  the 
  bodies 
  seen 
  in 
  

   Fig. 
  A 
  (6) 
  and 
  spores 
  ceases. 
  Besides 
  the 
  very 
  important 
  facts 
  

   that 
  they 
  are 
  not 
  enclosed 
  in 
  a 
  definite 
  oocyst 
  and 
  are 
  still 
  

   within 
  the 
  host-cell 
  (the 
  former 
  of 
  which, 
  at 
  any 
  rate, 
  would 
  

   be 
  without 
  analogy 
  in 
  the 
  order), 
  there 
  is 
  another 
  reason 
  why 
  

   these 
  bodies 
  cannot 
  be 
  regarded 
  as 
  representing 
  true 
  spores. 
  

   This 
  is 
  their 
  varying 
  and 
  indefinite 
  shape 
  — 
  or 
  rather 
  their 
  

   shapelessness, 
  — 
  together 
  with 
  the 
  extremely 
  delicate 
  nature 
  

  

  