﻿162 
  H. 
  M. 
  WOODCOCK. 
  

  

  differentiation 
  in 
  anotlier 
  direction 
  whicli 
  is 
  not 
  met 
  with 
  in 
  

   Gary 
  otroplia. 
  In 
  tlie 
  latter 
  there 
  is 
  no 
  sign 
  of 
  an 
  early 
  

   diiferentiation 
  of 
  sexuality. 
  The 
  nierozoites 
  (representing* 
  

   the 
  end 
  term 
  of 
  schizogony), 
  which 
  grow 
  into 
  microgaraeto- 
  

   cytes 
  of 
  the 
  first 
  order 
  or 
  macrogametocyteSj 
  respectively, 
  

   are 
  in 
  no 
  way 
  different 
  from 
  the 
  indifferent 
  ones 
  which 
  become 
  

   ordinary 
  schizonts; 
  that 
  is 
  to 
  say, 
  there 
  is 
  no 
  male 
  or 
  female 
  

   schizogony 
  accompanied 
  by 
  the 
  formation 
  of 
  male 
  or 
  female 
  

   merozoites 
  such 
  as 
  we 
  find 
  in 
  certain 
  cases 
  (Adelea, 
  Cyclo- 
  

   spora). 
  Now 
  in 
  Klossiella 
  the 
  "glomerular" 
  form 
  men- 
  

   tioned 
  above 
  almost 
  certainly 
  represents 
  either 
  male 
  or 
  female 
  

   schizogony, 
  leading 
  to 
  gametocyte-formation, 
  and 
  this 
  view 
  

   is 
  supported 
  by 
  the 
  authors' 
  remark 
  that 
  the 
  phase 
  was 
  only 
  

   found 
  in 
  kidneys 
  already 
  strongly 
  infected 
  with 
  the 
  other 
  

   stage, 
  i. 
  e. 
  when 
  merogony, 
  we 
  may 
  assume, 
  had 
  almost 
  run 
  its 
  

   potential 
  course. 
  In 
  the 
  absence 
  of 
  any 
  further 
  knowledge 
  of 
  

   the 
  parasite 
  it 
  is 
  impossible 
  to 
  say 
  with 
  certainty 
  which 
  sex 
  

   the 
  lozenge-shaped 
  bodies 
  above 
  described 
  represent; 
  whether, 
  

   in 
  other 
  words, 
  they 
  will 
  grow 
  into 
  micro- 
  or 
  macrogameto- 
  

   cytes. 
  Smith 
  and 
  Johnson 
  are 
  inclined 
  to 
  think 
  they 
  may 
  

   become 
  the 
  former, 
  and 
  suggest 
  that 
  they 
  give 
  rise 
  to 
  the 
  

   actual 
  gametes 
  onlj'- 
  when 
  attached 
  (" 
  accoles 
  ") 
  to 
  a 
  female 
  

   element; 
  they 
  did 
  not, 
  however, 
  observe 
  this 
  process 
  taking 
  

   place. 
  Their 
  shape 
  somewhat 
  recalls 
  that 
  of 
  the 
  male 
  mero- 
  

   zoites 
  of 
  A. 
  mesnili 
  as 
  figured 
  by 
  Perez 
  (3). 
  Whether, 
  if 
  

   we 
  accept 
  these 
  as 
  male 
  elements, 
  the 
  female 
  merozoites 
  

   (becoming 
  macrogametocytes) 
  are 
  similar 
  to 
  the 
  indifferent 
  

   ones 
  (as 
  in 
  A. 
  mesnili, 
  again), 
  and 
  whether 
  they 
  are 
  formed 
  

   in 
  the 
  same 
  complicated 
  manner, 
  or 
  by 
  simple 
  schizogony, 
  

   are 
  facts 
  which 
  have 
  still 
  to 
  be 
  ascertained. 
  In 
  any 
  case 
  the 
  

   rediscovery 
  of 
  Klossiella 
  muris, 
  and 
  the 
  working 
  out 
  of 
  

   its 
  complete 
  life-history, 
  would 
  probably 
  furnish 
  some 
  very 
  

   interesting 
  and 
  important 
  additions 
  to 
  our 
  knowledge 
  of 
  the 
  

   Coccidia. 
  

  

  