﻿EPITHELIAL 
  ISLETS 
  OF 
  THE 
  PANCREAS 
  IN 
  TELEOSTEI. 
  395 
  

  

  cell. 
  The 
  elements 
  were 
  small, 
  and 
  resembled 
  tlie 
  Uglitly 
  

   staining 
  or 
  polyhedral 
  forms. 
  They 
  presented 
  in 
  their 
  finer 
  

   structure 
  no 
  features 
  of 
  a 
  special 
  nature. 
  

  

  The 
  conditions 
  observed 
  in 
  Anarrhicas, 
  Onos, 
  Cyclo- 
  

   pterus, 
  Zoarces, 
  Arnmodytes, 
  Pleuronectes, 
  and 
  Hip- 
  

   poglossus, 
  it 
  willbe 
  noted, 
  are 
  suggestive 
  of 
  a 
  double 
  tissue 
  

   within 
  the 
  islet. 
  No 
  such 
  appearance 
  is 
  observable 
  in 
  the 
  other 
  

   forms 
  examined. 
  Massari 
  describes 
  a 
  two-fold 
  tissue 
  in 
  

   An 
  gu 
  ilia, 
  distinguishing 
  the 
  two 
  kinds 
  of 
  cell 
  as 
  " 
  chromato- 
  

   phile 
  " 
  and 
  " 
  achromatopbile.'^ 
  Diamare 
  has 
  sought 
  to 
  refute 
  

   this 
  view, 
  his 
  interpretation, 
  as 
  already 
  indicated, 
  being 
  that 
  

   the 
  differences 
  seen 
  are 
  indications 
  of 
  different 
  functional 
  

   states 
  in 
  the 
  two 
  regions, 
  and 
  that 
  there 
  is 
  one 
  tissue 
  only. 
  

  

  It 
  is 
  satisfactory 
  to 
  note 
  that 
  on 
  the 
  point 
  at 
  issue 
  there 
  is 
  

   a 
  remarkable 
  agreement 
  even 
  in 
  some 
  matters 
  of 
  minute 
  detail 
  

   as 
  to 
  the 
  actual 
  conditions. 
  Diamare's 
  paper 
  did 
  not 
  reach 
  

   me 
  until 
  after 
  my 
  own 
  observations 
  were 
  made, 
  and 
  although 
  

   the 
  species 
  examined 
  were 
  not 
  the 
  same, 
  and 
  his 
  methods 
  of 
  

   fixation 
  and 
  staining 
  were 
  different 
  and 
  more 
  varied 
  than 
  

   mine, 
  all 
  the 
  appearances 
  noted 
  by 
  him 
  are 
  to 
  be 
  seen 
  on 
  my 
  

   own 
  preparations. 
  The 
  question 
  is 
  largely 
  a 
  matter 
  of 
  inter- 
  

   pretation 
  of 
  results. 
  

  

  The 
  facts 
  are 
  briefly 
  these. 
  Tracts 
  of 
  more 
  or 
  less 
  

   columnar 
  or 
  fusiform 
  cells 
  wind 
  through 
  the 
  islets, 
  and 
  

   around 
  and 
  between 
  these 
  are 
  slightly 
  larger 
  polyhedral 
  cells 
  

   arranged 
  in 
  masses. 
  The 
  columns 
  stiiin 
  more 
  darkly 
  than 
  the 
  

   masses. 
  Diamare 
  speaks 
  of 
  tracts 
  showing 
  intermediate 
  

   staining 
  which 
  force 
  the 
  suspicion 
  that 
  they 
  do 
  not 
  represent 
  

   two 
  different 
  categories 
  of 
  cells. 
  I 
  myself 
  found 
  islets 
  in 
  

   which 
  the 
  contrast 
  in 
  the 
  two 
  types 
  was 
  less 
  marked 
  than 
  in 
  

   others, 
  but 
  even 
  here 
  it 
  is 
  deserving 
  of 
  notice 
  that 
  the 
  columns 
  

   were 
  always 
  darker 
  than 
  the 
  masses. 
  If 
  a 
  difference 
  of 
  

   functional 
  state 
  be 
  indicated 
  by 
  these 
  appearances, 
  we 
  expect 
  

   the 
  columns 
  will 
  at 
  some 
  time 
  show 
  the 
  lighter 
  staining 
  

   effect, 
  and 
  also 
  that 
  the 
  polyhedral 
  cells 
  will 
  be 
  found 
  in 
  the 
  

   darker 
  phase. 
  Such 
  conditions 
  were 
  not 
  found 
  by 
  me. 
  

   Diamare, 
  further, 
  makes 
  much 
  of 
  the 
  fact 
  that 
  the 
  one 
  type 
  

  

  