188 Dll. BEALE^ ON THE TISSUES. 



rine, and magnified 130 diameters. The smaller vessels 

 could not be discerned. Nuclei were seen, but very indis- 

 tinctly, and in smaller number than they existed. The want 

 of definiteness about the structure would cause one to 

 conclude that, in this specimen, areolar or connective tissue 

 predominated over every other tissue; and that the nuclei 

 were connected with the fibres of the areolar tissue, although 

 an absolute connection between the fibres and nuclei could 

 not be seen. No. 4. Another specimen from the central part 

 of the tongue" of the mouse, from the same part as the last 

 section, but injected and soaked iu carmine. The ''^con- 

 nective tissue^' of the last specimen was seen to contain 

 numerous capillaries and nerve-fibres. The nuclei seen in 

 the section were clearly connected with the nerves and 

 capillaries. Nerve-fibres, not more than the one ten thousandth 

 of an inch in diameter, could be traced to and from the 

 ganglion. The nuclei on the surface of the ganglion, usually 

 considered as the nuclei of the connective tissue surrounding 

 its cells, belonged to the nerve-fibres growing from the cells. 

 This specimen was magnified 250 diameters. 



There is, however, no organ which shows the importance 

 of different processes of preparation in so marked a manner 

 as the liver. 



On the termination of the hepatic ducts. — Upwards of six 

 years ago, Dr. Beale succeeded in injecting the ducts of the 

 liver, and believed that he had demonstrated that the ducts 

 were continuous with tubes containing the liver-cells. He 

 regarded the liver as the most perfect type of gland, because 

 the largest quantity of secreting structure and blood were 

 brought into the closest relation, while they occupied the 

 smallest possible space. The prepuic.tions proved that in- 

 jection passed directly from the ducts into a network of tubes 

 with very thin walls, which were occupied with the liver-cells. 

 The coloured injection passed between the cells and the walls 

 of the tube, insinuating itself through very narrow channels, 

 but nevertheless forcing its way along for a considerable 

 distance, and sometimes it reached the centre of the lobule. 

 As injection could be forced thus artificially in a direction 

 the reverse of that in which the bile flows during life, the 

 possibility of the bile flowing between the walls of the tube 

 and the cells was fully proved. These conclusions were 

 published in a paper in the '^Phil. Trans.,' in 1856; and, after 

 an interval of several years. Dr. Beale could now speak with 

 far greater confidence. 



Professor Budge, of Greifswald, has curiously distorted 

 one of Dr. Beale's drawings. He (Dr. Beale) did not believe 



