DR. BEALE, ON THE TISSUES. 189 



that any one who was himself accustomed to microscopical 

 work would have considered that the merest tyro could have 

 made such a mistake as the one which he was credited with 

 by Professor Budge. He exhibited his own drawing of the 

 specimen, and Professor Budge's inference from the drawing 

 of the appearance of the specimen, which he had never seen, 

 and the preparation itself. Specimens, No. 5, preserved for 

 seven years was then sent round. It was magnified 215 di- 

 ameters. The blue injection was shown amongst the cells in 

 the tubes, and not the faintest indication of the tubes around 

 each cell delineated by Professor Budge, was to be seen. 

 No. 6. A corresponding preparation from the human liver, 

 magnified 130, showing the ducts just at the edge of a lobule, 

 and their continuity with the tubes of the cell-containing 

 network. — No. 7. Also from the human liver, showed the 

 capillaries injected blue, and the cell-containing network 

 alternating with them, and having in all parts of the lobule 

 exceedinglj^ thin walls, but quite distinct from the capillaries. 

 This preparation was magnified 215. 



Perhaps, however, the most perfect demonstration of the 

 cell-containing network, and its continuity with the ducts, is 

 obtained from the examination of the liver in cirrhosis, in 

 which disease the cells and tubes shrink, the change com- 

 mencing at the portal aspect or circumference of the lobule, 

 and proceeding gradually towards the centre. — No. 8. A 

 section of a healthy liver under an inch object-glass. The 

 portal vein was injected with carmine, and the hepatic vein 

 with Prussian blue. The capillaries of the lobule were filled 

 with the colouring matter — those in the centre of each lobule 

 being blue, while those at the circumference are red. The 

 interlobular fissures were very narrow, and in many places 

 the capillaries of one lobule were continuous with those of 

 adjacent lobules. The interlobular spaces were clearly 

 destitute of any areolar or fibrous tissue. They were occupied 

 by branches of the portal vein, and branches of the artery 

 and duct, and lymphatics, which had not been injected in 

 this specimen. — No. 9. A specimen of cirrhose liver in which 

 the vessels had also been injected. Here a wide space existed 

 between the contiguous lobules, of which but very little, and 

 only of the central part of the lobule, remained in many 

 cases. Vessels and tubes were observed in the substance of 

 the tissue usually stated to be fibrous. — No. 10. A specimen 

 of a cirrhose liver, magnified 130, soaked in carmine. The 

 shrivelled cells could be seen within the narrowed tubes, and 

 the network was very distinct. — No. 11. A specimen from 

 the same liver put up in water. Not a vestige of anything 



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