194 1>R. BEALEj ON THE TISSUES. 



every particle of albumen^ casein, fibrine, 8cc., is produced 

 under conditions which can only exist in living particles. 



Of nuclei and nucleoli. — In many cases, certain of the 

 particles of the germinal matter grow more slowly than 

 others, and remain perhaps for a long period in a compa- 

 ratively quiescent state. These masses are generally spherical 

 or oval, and they have a power of resisting the action of ex- 

 ternal circumstances which would destroy the active portion 

 of the germinal matter. These are the so-called nuclei, and 

 from them new structures may spring, even if the germinal 

 matter in which they lie be destroyed. When they become 

 active, certain minute particles within them may become 

 new nuclei, while the particles of the original nucleus in- 

 crease and pass through the various stages of their active 

 existence, and at last become resolved into formed material. 

 Generally, when the conditions under which an elementary 

 part is placed are very favorable for the growth of the 

 germinal matter, the most rapid increase in size may be 

 observed to occur in the particles just within the envelope of 

 formed material; and not unfrequently numerous spherical 

 masses of germinal matter may be seen in close contact with 

 the membrane, and therefore as near as possible to the 

 nutrient matter. 



Secondary deposits. — In some cases, after a layer of formed 

 material has been produced externally, and the whole mass 

 has reached a certain size, certain particles of the germinal 

 matter become resolved into formed material, which collects 

 as one mass, or in the form of several separate particles, 

 which may accumulate amongst the particles of the germinal 

 matter. If this process continue for some time, the germinal 

 matter forms a thin laver between this mass of formed 

 material, which Dr. Beale proposed to call secondary deposit, 

 and the outer membrane or envelope of formed material, a 

 position in which the germinal matter (primordial utricle) of 

 the vegetable cell and that of the fat-vesicle (nucleus) are 

 found. 



Regarding a growing spore of mildew as an elementary 

 part, it consists externally of formed material, within which 

 is the germinal matter. Certain portions of the germinal 

 matter are not in a state of great activity like the remainder ; 

 and these are nuclei from which new growth may proceed, if 

 the formed material and the remainder of the germinal 

 matter should be destroyed. If there be no nuclei, no 

 future elementary parts could, under these circumstances, 

 be formed ; and the death of the germinal matter renders it 

 impossible that new structures can result from the mass. 



