4 ARTHUR BOLLES LEE 
into a theory of the quiescent nucleus lately, by Grégoire and 
his pupils (Grégoireet Wygaerts, ‘Ta Reconstitution du 
Noyau et la Formation des Chromosomes”’, ‘ La Cellule’, xxi, 
1908, p. 7; Grégoire, “Ta structure de |’élément chromo- 
gomique au repos et en division ”’, ibid., xxiii, 1905, p. 811; 
and other papers by himself and his pupils). According to this, 
the homogeneous chromosomes of the prophase become during 
the telophase honeycombed with numerous vacuoles or alveoles, 
which end by splitting each of them up into a mere network of 
chromatin. These networks then anastomose by lateral pro- 
cesses, and there is thus formed a network of networks, the 
reticulum of the quiescent nucleus. At the next prophase the 
anastomoses are drawn in, and homogeneous chromosomes are 
formed anew from the remaining reticular tracks by the 
obliteration of their alveoles and condensation of their honey- 
combed chromatin into a homogeneous thread. 
I have already (‘ La Cellule’, xxvin, 1918, p. 265) published 
a study of the essential points at issue between Grégoire and 
Bonnevie, as exemplified in the pollen grains of Paris qua- 
drifolia. I there found the chromosomes to be alveolated 
as described by Grégoire; but I did not find their alveolatioa 
to progress in the telophasic chromosomes to the pomt of 
breaking them up into networks. On the contrary, I found their 
alveoles to disappear, and the chromosomes to condense into 
thin spiral threads. But I did not find these threads to ana- 
stomose into a network in the resting nucleus, as described by 
Bonnevie. I found nothing worthy of the name of a network, 
but only a tangle of the much elongated and attenuated spiral 
chromosomes. J found these persisting throughout the inter- 
phase, and at the next prophase forming typical chromosomes 
by shortening and thickening and at the same time again 
becoming alveolated. Fig. 11 represents a typical group of 
1 This is a drawing of the anaphase shown in fig. 6 of my paper, amended 
by the addition of the sheath and lateral processes round the axis of the 
chromosomes, which had escaped me when the original drawing was made. 
I think it quite likely that there may be also a very fine periaxial spiral, in 
correspondence with the lateral processes, round the axis of the chromo- 
