( 672 ) 
with the samples was bound by the alkali and, also because the 
the quantity was relatively small, it did not disturb the development 
of the colonies, as appeared from control experiments. 
In the graphical representation of the results, to render a mutual 
comparison easier, a number of 1000 living germs has been started from 
and the values found experimentally have been reduced accordingly. 
As proceeds from the figures, the type of the “curves of survivors’ 
is in our disinfection-experiments with phenol quite similar to the 
one which was found in dying off by heat; very clearly the \ 
form is again to be recognized in it. 
200 
700 
Ar 
(am 
Bac. coli 
1000 PES 
£ 900 
2 800 
ee AD 
So 600 
=. S00 
< 
El 400 beki as BS 
ae 0 
6 
oO 
Ler} 
5: 
lal 
LV 
S 
N 
2% 
bo 
B 
| 
oO 
en! 
Co 
Nay 
as 
S 
Nv 
172.73 14.13 
Minutes 
Fig. 1. 
As in our experiments nothing has been left undone to put all 
the individualls, both in the process of incubation and that of 
disinfection, under quite the same conditions, a very marked accumu- 
lation of deaths might have been expected on either side of an 
average. In reality, however, this was not the case (most, though, 
with a in fig. 1) and again considerable differences of resistance 
between individuals of the same culture came to light. For this I 
see no other explanation, though it remains for the present only a 
mere supposition, than that the power of resistance during the 
development between two successive divisions undergoes changes. 
It may for example be imagined that under for the rest equal 
circumstances a daughter-cell just formed is, on account of her relatively 
‘larger surface, more vulnerable than a full-grown cell. 
And because the length of generation is relatively short, amounting, 
in strong multiplication, to less than half an hour, all stages of 
development will occur by the side of each other. 
