1342 
by A. Biepr. In addition to the connection between the function 
of the cortex and that of the sexual organs, also the possibility of 
an antitoxic action of the adrenal cortex has been empbasized. In 
the latest edition of his Manual of Internal Secretion Brepu still 
considers it as an open question whether, just as Cobra-poison in 
vitro, also endogenous poisons can be counter-acted by adrenal- 
cortex. 
It seems to me that the result of adding small quantities of 
adrenal cortex to the Daphnia cultures — in the case of over- 
population and of mould infection — indeed points to an inhibitory 
influence on the action of normal metabolic products. It is notable 
that this occurs in lower organisms, which, so far as we know, 
do not possess an organ corresponding to the suprarenal capsule of 
the vertebrata. ; 
Our deficient knowledge of the normal function of the adrenal 
cortex justifies a further inquiry of this problem in different directions. 
