1351 
quickly to the normal values. The chamber-liquid follows these 
changes more slowly, here probably abnormally slowly, because, as 
a second adrenalin-action, the blood-supply to the eyes had decreased 
very considerably for the time being. Thus, for example, the sugar- 
percentage in the bloodplasm rose in 30 minutes from 0.25 °/, to 
0.38 °/,, in the chamber-liquid (first in the right eye, then the left) 
it rose in the same time from 0.17 °/, to 0.24°/,; in another expe- 
riment the sugar-percentage in the bloodplasm had increased in 2 
hours after the injection from 0.21 to more than 0.6 °/,, in the 
chamber-liquid from 0.19 °/, to 4°/,; the rapidly regenerating secondary 
chamber-liquid then contained 0.63 °/, which corresponds strikingly 
to the bloodplasm at that moment. 
When in the second period the sugar-percentage of the blood- 
plasm decreases, this decrease is followed more rapidly by the 
chamber-liquid than the increase which preceded. This is to be 
expected because in this period the blood-supply to the eyes and 
consequently the rapidity of diffusion has become greater. Yet we — 
succeeded in establishing a moment when the decrease in blood- 
sugar-percentage outstripped the chamber-liquid, so that the relations 
were reversed: 5 hours after the injection the sugar-percentage of 
the plasm was 0.27°/,, that of the chamber-liquid was 0.32°/,. 
It might also be possible to explain the great difference (0.6 and 
0.4) which was established at the culminating-point of the hy per- 
glycaemia, not by means of retarded diffusion (consequently : equili- 
brium not yet reached), but by a relative increase also of the combined 
sugar during the hyperglycaemia. The difference of 0.2°/, could then 
correspond to the quantity of combined sugar and the 0.4°/, sugar 
in the chamber-liquid would indicate the moment of the equilibrium 
of the diffusion. But this supposition is no longer valid, for during 
a separate experiment we have, (during the maximum of hyper- 
glycaemia) taken off a slightly larger quantity of blood and we have 
determined the sugar-percentage of this together with the sugar- 
percentage of the ultra-filtrate, obtained from it; the same had been 
done before with the normal blood-plasm. In the beginning the 
sugar-percentage of the chamber-liquid was 0.24, of the blood-plasm 
it was 0.26 and of the ultra-filtrate of the plasm it was 0.16; the 
difference between the last two is therefore 0.09. This difference 
now remained equal during the adrenalin-hyperglycaemia (0.63°/, 
and 0.54°/,), while then the sugar-percentage in the chamber-liquid 
was much lower (0:44°/,) than that in the plasm. Hence the quantity 
of combined sugar does not increase during adrenalin-hyperglycaemia. 
It will strike that in vitro in this experiment we find a quantity 
