1166 
The fact that in the oxidation of d-gluconamide with sodium 
hypochlorite sodium isocyanate is also formed was demonstrated by 
addition of hydrazine sulphate, neutralisation and subsequent addition 
of benzaldebyde. 
The precipitate formed contained beside benzalazine, benzalse- 
miearbazone, which were separated by means of ether. 
Degradation of d-galactose. 
d-galactose was degraded in exactly the same way to d-lyxose. 
NH, 
Cu CO CH 
HOH H | OH HO | H 
HO | H HOH HO |H 
— — 
HO H HO H HOH 
HOH H OH 
Hs I, Ha 
Cor Con Cor 
d-galactose d-galactonamide d-lyxose 
The d-lyxose was isolated as parabromophenylhydrazone, *) Melting 
puint 156°—157°. 
0,1488 gram gave 11,3 c.c. N at 16° C. and 762 m.m. 
Found: 8,83 °/, N. 
Calculated for C,,H,,0O,N, Br.: 8,78 °/, N. 
On mixing it with a specimen of p-bromophenylhydrazone from 
d-lyxose, prepared according to Rurr’s method, and which I likewise 
received from the laboratory at Amsterdam, the melting point remained 
unchanged. 
I want to point out that the preparation of the amides of the 
pentonie and the hexonic acids is easy of execution, as the lactones 
need not be isolated in a crystallised condition. For instance, from 
the calcium salt of d-galactonie acid I obtained a yield of 95°/, of 
d-galactonamide. Mannonamide and arabonamide are also readily 
formed in this manner. With gluconamide the yield is less favourable 
because the formation of the lactone does not take place normally *). 
1) ALBERDA VAN EKENSTEIN and BLANKSMA, Chem. Weekbl. 11, 191 [1914]. 
Levene and La Fores, Journ. of Biol. Ch. 18, 325 [1914]. 
2) Ner, Liepie’s Annalen 403, 322 [1914]. 
