1335 
In view of this agreement between phagocytes 
and respiratory centre the question suggests 
itself whether other substances have likewise 
the same effect on both. 
Therefore we have in the first place investigated the effect of 
carbonic acid on phagocytosis. Some years ago already we published 
investigations on the effect of CO, on phagocytes, and arrived at 
the conclusion that the use of somewhat large amounts of CO, had 
an injurious effect on phagocytosis’). The effect of slight quantities 
was not investigated then. 
Now that we had a more accurate methode at our disposal, it became 
desirable to repeat the experiments with slighter quantities of CO, 
NaCl-solutions were made with different CO,-percentages by 
mixing different quantities of a boiled out NaCl-solution with the 
same NaCl-solution which had been saturated with CO, 
We prepared the following mixtures: containing 
4 Vol. NaCl-sol. + 1 Vol. of the NaCl-sol. saturated with CO... 85 Vol. pet CO, 
ons": F Sparkle VOL Ns - 7 jd EIN oet ers 
19 ” ” = 1 Vol. ” ” ” ” ” ” 8.75 ” „ El 
KO 5 ioe Wy Olas! 45 8 2 3 5 Set ven 
99 2 ” oe 1 Vol. ” 9. ” ” ” ” 1 75 „ 9 „ 
TABLE IX 
Effect of CO, on phagocytosis. 
Boiled out NaCl-sol. | Phagocytosis 
containing : | 
no CO, 46.3 % 
go Vols” Perc, “CO, 0 
ae ' pe 0.7 % 
8.15, 5 ABe 
3, ; 7 A 
V's; 8 ” 4215 
This table shows that carbonic acid has effected an entire or 
entire paralysis of the phagocytosis, except in the concentrations 
3.5 °/, and 1.75 °/,. 
1) Hampurger. Virscnow's Archiv 156 (1899), 329. 
