864 



the contractions returned during this increased tonus. This tonus- 

 increase was likewise of a short duration. Afterwards an addition 

 of H,0, had no longer any effect. 



This suggested the question whether perhaps H,0, is decomposed 

 by CHCl,. Therefore a parallel experiment was carried out. Two 

 glasses with a solution of H^O, 1 : 17000 in Tyhode's fluid were 

 heated to 37° and kept at this temperature during the experiment. 

 To one of the glasses was added a CHClj-solution so that its con- 

 centration became 1 :1500. 



Nil 



In the following table the ciuantitv in cc of KMnO, has been 



'1000 



given, necessary to neutralize 25 cc. of the solution. 



It becomes evident that the amount of H,0, decreases equally 

 in both glasses, so that most likely a decomposition of chloroform 

 by H,0, will be out of the question. 



Some experiments were carried out on the effect of another 

 oxydating substance viz. K,FeCyg. Just as in the case of the phago- 

 cytes no favourable, result could be obtained. Not even in the 

 presence of CO,, whicii might lead us to expect a quicker penetration 

 into the cells. 



SUMMARY. 



In very weak concentrations (sometimes 1:1300000) H,0, acts 

 upon the intestine. Tliis action chiefly consists in an increased tonus 

 during a shorter or longer time. This tonus-increase likewise sets 

 in when H^O, acts upon the narcotized intestine. 



We intend to discuss on some future occasion the significance 

 and the meaning of this H,0,-action. 



October 1917. Physiological Laboratory 



in the University of Groningen. 



