( 626 ) 
Attempts with Dr. FrIEDMANN to prepare it from diaminoacetone 
hydrochloride, although not having led to the desired result, still 
showed that a substance obtained by RtGuumer in 1892 by the 
action of chloroformic ester on diaminoacetone and which he supposed 
to be acetone-ureine, although no analysis of it was made, can have 
been nothing else than acetonediurethane. 
We have now continued these investigations and have succeeded 
in elucidating the reaction with potassium isocyanate, although this 
also has not led to the desired result. Rüenwimer had pretended in 
1892 that a diureo-acetone would form which, however, was so 
unstable that he could not isolate the same and that it was converted 
at the ordinary temperature with loss of ammonia into a substance 
which he called acetonylbiuret*), in which he determined the carbon 
and hydrogen but not the nitrogen; at least he does not give the 
percentage. Had he done so, he would probably have found that it 
possesses quite a different composition, not C,H,O,N, as he states, 
but C,H,O,N, which we have found for the compound formed by 
the action of two mols. of potassium isocyanate on one mol. of 
diaminoacetone hydrochloride in aqueous solution. By the action of 
one mol. of isocyanate, a chlorinated substance, having the composition 
C,H,ON,Cl, is formed, which on being treated with a second mol. 
of isocyanate, yields the first product. In consequence of the analogy 
with a number of other well-known reactions we take it for granted 
that as soon as a ureo-group has formed, this acts with its NH,- 
group on the CO of the acetone residue, when a cyclic compound 
is generated with formation of water. 
The following formulae will have to be assigned to the two com- 
pounds obtained; although other ones might be proposed, they are 
amply confirmed by the derivatives obtained. 
GEEN GENE 
| De | nt 
| JD | JO 
C Ne Ee! 
| | 
CH NHS OO ENE CH NEE 
Ureopropyleneureïne. Aminopropy leneureine 
hydrochloride. 
‚CHs. NH. CO 
fe : 
1) To which he assigned the formula CO NNH. 
Nen. NH. CO 
