( 983 ) 
AR BOL ES) K 
Effect of lodoform on phagocytosis. 
Percentage of leucocytes having 
Time during, taken up carbon. 
which the 
leucocytes The leucocytes are 
wereallowed Theleucocytes are in a saturated sol. 
to take u of lodoform in 
rn ‘ in NaCl 0,9, NaCl 0.9 /, 
(1 to 100.009) 1) 
152) 2515 
/ Mi | | nee / >) | hi FR. 2:0/ 
10 minutes 424 X 100 = 40,8 | Fears 100 = 56,89, 
, 185 ek | 905 . nas 
= e 34 ALOE p | 106” ierk 
236 : 286 Teens 
30 5 r 2 100 == ade, | 42 COD == 69 
304 ee hee 356 a 
7 — == QS nd \ (0 
I hour 520 2< LOOSE 3 we ie 
402 HIS 4 
11/, ” 507 S 10067, ” Eden a 70,1 ” 
This table shows that after 10 minutes in the pure NaCl-sol. 0.9°/, 
40.8°/, of the leucocytes had taken up carbon, but in the NaCl sol, 
containing Iodoform 56.8 °/,. 
After 20 minutes the values are 54°/, and 61.4°/, respectively. 
Hence it appears that Lodoform promotes phagocytosis to a considerable 
extent. After 1'/, hour the values are: 67.3°/, and 70.1 °/,. 
We may infer from this that after that time the extent of phago- 
eytosis has become about equal. 
The same facts had been observed before when we studied the 
effect of Calcium on phagocytosis. As we did then*) we may also 
conclude now that the effect of lodoform is based upon an acceleration 
of the amoeboid motion, and not upon a greater development of 
activity (energy) of the phagocytes, rendering cells which under 
normal circumstances would be too weak to take up particles, capable 
of doing so by the presence of lodoform. For if this were the case 
the phagoeytosis would remain considerably lower in the pure NaCl 
sol. than in the NaCl sol. containing lodoform. But after 1°/, hour 
1) See page 986. 
2) This means that of the 424 leucocytes counted, 173 had taken up carbon, 
5) Proceedings June 9th 1910. 
