( 990 ) 
3. in the old iodoform solution the phagocytosis amounts to nothing, 
whereas in a solution, which contains only one third of the old 
iodoform solution, it has increased to 12.7°/,. 
From these experiments it may be coneluded that not the ion of 
iodine but Iodoform as such, causes the increased phagocytarian 
power. 
And now the question suggests itself: how can the favourable 
effect of iodoform upon the rapidity of the phagocytarian process 
be explained ? 
We must obviously think here of a decrease im the surface-tension 
which facilitates the amoeboid motions of the protoplasm. 
It is not diftieult to account for this decreased surface-tension if 
we consider that iodoform is soluble in fat substances and that, as 
may be concluded from numerous investigations, the outer layer of 
cells consists of a fat substance, a so called lipoid membrane. 
Further it is obvious that such a lipoid membrane will grow more 
flexible after having absorbed iodoform, in other words that the 
surface tension will decrease, and that consequently the amoeboid 
motion will be facilitated. 
If this interpretation was the correct one, then it might be expected 
that also other substances, which are soluble in fat, such as chloro- 
form, Benzene, Camphor, would ajject phagocytosis in a similar way. 
As will appear from the following experiments, this was indeed 
the case. 
2. Errect oF CHLOROFORM ON PHAGOCYTOSIS. 
It might be expected that, besides an accelerating effect by weaken- 
ing the outward lipoid layer, chloroform would have a paralyzing 
effect, opposed to the former, viz. on the protoplasm of the phagocytes. 
Therefore various dilutions bad to be tried. 
Soon it was found that dilutions of 1 to 2000, 1 to 6000 and 
also 1 to 10000 impair phagocytosis. The following table VIII con- 
tains some experiments with weaker dilutions. 
From this table it appears that chloroform 1 : 20000 raises the 
phagocytarian power from 40.9°/, to 50.4°/,, further that phagocytosis 
is considerably increased by chloroform 1: 100000; there it rises 
fo0-60;5 2); 
dvidently in the chloroform-solution 1 to 20000 the above men- 
tioned paralyzing influence also makes itself felt. 
In a dilution of 1: 500.000 the favourable effect remains, to about 
he same extent as in 1: 100.000, and finally in a solution of 1 
