(oe 
BaP BART M Ee, SNP.) 6, 
Grote 6: Goat D. 
Mouse Date Subcut. Result Mouse Date Subcut. Result 
| 
N°. 462 3 Nov. 2.0c.c. serum N°. 464 3 Nov. 2.0c.c. serum 
Bs 0.3cc. toxine FT 0.3 c.c. toxine 
We. | local tetanus Bt no symptoms 
Oe je dead nja no symptoms 
Tes os. no symptoms 
8 „ oy no symptoms 
N°. 463 | 3 Nov. | 2.0c.c. serum N°. 465; 3 Nov. 20c.c. serum 
As 0.3 c.c. toxine A 0.3 c.c. toxine 
Gn | local tetanus Eens no symptoms 
eer dying 0% no symptoms 
et | dead shaw das | no symptoms 
Ss San no symptoms 
CONTROL. | 
Mouse Date Subcut. Result 
| 
N°. 466! 4 Nov. 0.3c.c. toxine 
OE And local tetanus 
Gs, dead 
day after the immunization both goats were bled and the anti- 
toxic potency of their serum was compared. 
As it appears from the experiments 4, 5, and 6, the results were 
quite conformable to those we got for goats A and B. 
The result of the experiments mentioned above, shows clearly 
that, to tix the dosis of an immune serum which has to be injected 
to acquire an immunity of a certain degree and duration, not only 
attention has to be paid to the titre of the serum, as now generally 
happens, but also to the quantity. The quantity may not be chosen 
too small, because the organism defends itself against the heterolo- 
