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of Keimschläuche is less preferable) 5. medullary cords which contain 
egecells and at some places swell and develop into vesicles, c. a 
great number of follicles with more than one eggcell. 
2. The atypical follicles are of twofold nature: there are ball- and 
cord follicles. 
3. In the normal development of the ovary, owing to proliferation 
of the connective tissue, the eggballs and medullary cords divide into 
primary follicles, shortly before or soon after birth. In the preparation, 
described before, the development of the connective tissue was 
apparently insufficient. 
4. It is possible that the large follicles occurring in old foetusus 
and in infants arise from the medullary cords. This is possible, 
because larger parts of the medullary cords develop into vesicles, 
but these may also originate from the primary follicles, which in 
normal circumstances originate from the medullary cords. 
It is doubtful whether the opinion of Runer (that these vesicles 
contain eggcells fit for fecundation) is right, taking into consideration 
the genesis (medullary cord is homologous with the seminiferous 
tubules) and considering all we know on this subject in animals. 
The formation of vesicles from the medullary cords in the above- 
mentioned preparation, points to a disturbance in the development 
(a process, normally taking place at a very early age, found in an adult). 
5. Normal vesicles may be developed from atypical ones by 
reduction of all the cells (Nebeneier) except one (Hauptei). 
6. It is impossible to state whether the eggball or the cord follicle, 
or both can give rise to plurigravidity. In this case one ought to 
know whether the cord follicles are actually ripening to maturity. 
Amsterdam. Histological Laboratory. 
