771 
The large lipochrome-content of adrenal and liver proves that 
these organs do not owe their pigment simply to the deposition of 
the coloured body fat in their tissues. There must be some elective 
affinity of these tissues for the lipochrome. 
2. With a single exception (N°. 6) considerable amounts of pigment 
were found in the organs also in those cases in which no lipo- 
chrome could be demonstrated in the blood. We will give a single 
instance: in patient N°. 40 a rather high value was noted for the 
adrenal, whereas the blood was free from pigment. In other cases 
(N°. 3) low values are found in all tissues, in number 6 even next 
to nothing. No rule can be discovered for the relations of the lipo- 
chrome-content of the various tissues. 
According to the data at our disposal a slight lipochrome-value 
of the blood is to be attributed first of all to the use of lipochrome- 
poor food. Since we often find low blood-pigment values by the side 
of normal or high organ-values, the conclusion must be made that 
these organs (particularly the liver and the adrenal) pertinaciously 
hold fast the pigment when lipochrome-poor food is taken. 
3. It is impossible to detect a relationship between the nature of 
the diseases and the amount of lipochrome in the blood or in the 
tissues. The high values in the case of diabetes are accounted for 
by the peculiar diet. 
4. The rise of the pigment-content of the blood with a lipochrome- 
rich diet, and the fall with a pigment-poor diet, warrants the conclu- 
sion that the organism derives these pigments from the vegetable 
kingdom (directly or indirectly through the use of animal food, 
which also owes these lipochromes to the vegetable kingdom). The 
blood absorbs these pigments and deposits them in the tissues. 
We are still wholly ignorant of their fate there. It might be supposed 
that they are accumulated by the fat, the adrenal, and the spleen, 
ad infinitum. This, however, does not seem likely, as in that case 
_the lipochrome-masses in the tissues of elderly people, would amount 
to enormous values, considering the large quantities of lipochrome 
taken up every day. So far as we were enabled by our data, we 
have arranged our results according to age. The number of cases is 
too small to draw conclusions from. Still, the inference may be drawn 
that, broadly speaking, children under 10 years of age present lower 
values than elderly people. However, we have not been able to 
ascertain, whether the values rise regularly with age and there is 
no question of elderly people presenting excessive values. 
50 
Proceedings Royal Acad. Amsterdam. Vol. XXIII. 
