2 



È. F. VAN DE Sandk Bakhiiyzf.n : "On the significance of the term in the Right Ascension 



of tlie moon, found by J. E. uk Vos van Stkenwijk, p. 144. 

 W. J. II. Moil: "A rjuick roil gnlvanometer'. (Commiuiioatf d by Prof. W. H. Jiiluts}, 



p. 149. 

 P. van Leersum : "v)ji the presence of quinine in the seed of Cinchona Ledgeriana Moens." 



p. 153. (With one plate). 

 F. Zeeman : "The red lithium line and tlie spectroscopic determination of atomic weights", 



p. 155. (With one plate). 

 H. U. WOLTJER and P. Zeeman : "Magnetic repolulion of spectrum lines and temperature", 



p. 158. 

 Ernst Cohen and G. ue Bruin : "On a new principle for the direct determination of osmotic 



pressure", p. ICO. 

 Ernst Cohen and G. de Bruin: "The influence of pressure on the E. M. F. of the lead- 

 accumulator", p. IGI. 

 0. J. C. van Hoogenhuyze and J. Niewenhuyse: '^Influence of alcohol upon the respiratory 



exchange during rest and during muscular exercise". (Communicated by Prof C. Eykman;. 



p. 164. 

 E. Hekma : '"On fibrin in sol and gel state. Likewise a contribution to our knowledge of tiie 



blood-coagulation problem". (Communicated by Prof. II. J. IIamburger). p. 172. 

 C. T. van Valkenburg and L. II. ,1. Mestrom: "On the optical centra of an anophthalmos" 



(Communicated by Prof. C. Winkler), p. 18G. 

 A. Smits : "The passivity of metals in the light of the theory of allotropy". (Communicated 



by Prof. A. F. IIolleman), p. 191. 

 A. F. HoLLEMAN : "The nitration of toiuols and its derivatives chlorated in the side-chain", 



p. 192. 



Physiology. - - ''Investicjations into the internal secretion of the 

 pancreas". By N. Waterman M. D. (Communicated by 

 Prof. C. A. Pekelharing). 



(Communicated in the meeting of February 22, 1913). 



In the following paper we shall attempt to summarize some series 

 of experiments in eonnection with the internal secretion of the pancreas, 

 which, though highly probable, is still a matter of conjecture. 



!•'' Series {A). 



Upon evidence with which we need not here concern ourselves, 

 it has been concluded that tlie pancreas subserves the carbohydrate 

 metabolism through some product of internal secretion. This being 

 admitted it is quite natural that we shonld be induced to ascertain 

 whether stimulants that increase the activity of this organ, also exert 

 an action on the carbohydrates of the organism. 



Among the agents that considerably promote the function of the 

 pancreas we selected the most potent, viz. secretin, discovered by 

 Bayliss and Starung. Our experiments showed results that gave rise 

 to the (|uestion whether we could trace any influence of secretin on 

 the amount of sugar in the blood. The fluctuations in this amount 

 were taken as an index of the changes in the carbohydrate meta- 

 bolism as the latter manifest themselves in the former. 



Kvperimeiits. 



1. Freparation of the secretin. 



Dogs, kindly procured by the "Society for the prevention of cruelty 



