TABEL IV 



\A/^;o-h* i Pancreas blood Supra- 



Weight I Jn.V^f^H I .onJn 



injected 



Blood- 

 sugar 



Urine in 24 hours 



Details 



20 2.8 K.G. 



21 jl.l „ 



22 jl 



23 1.25 „ 



24 1.3 ., 



I) i> 



25 



1.3 



I) I) 



26 12.2 



27 I 1.2 



28 1.25 



29 I 1.3 



5 cc serum 



5 „ (blood) 



4.5 

 10 

 10 

 10 



10 „ serum 

 20 „ blood 



20 „ heated 

 for half an hour 

 at 56° C. 



23 cc. liberated 

 from protein 

 with 3 X its 

 volume of alco- 

 hol 960'o and 

 evaporated doM^n 

 to its original 

 volume. 



0.5 m.g. 



0.5 „ 



0.5 „ 



0.5 „ 



0.5 „ 



0.5 „ 



0.5 „ 



0.5 „ 



0.5 „ 



0.5 ,. 



0.1950/0 



0.183 „ 

 0.156 „ 

 0.134 „ 

 0.189 „ 

 0.177 „ 

 0.153 „ 

 0.185 „ 

 0.145 „ 



0.151 .. 



40 cc a 6 '/2% glucose 



not collected 

 contains much glucose 

 40 cc a . 1 20/0 glucose 

 presence of glucose 

 40 cc + 

 > 30 cc a 0.30/0 

 50 cc a I.80/0 

 30 cc a I.680/0 



70 cc a 1.50/0 



Serum from pancreas 

 acted upon by secretin. 



Blood from pancreas be- 

 fore injection of secretin. 



Blood from pancreas 

 acted upon by secretin. 



Blood under the influ- 

 ence of secretin. 



Blood from pancreas be- 

 fore injection of secretin. 



Blood from pancreas 

 acted upon by secretin. 



Blood under the influ- 

 ence of secretin. 



Blood under the influ- 

 ence of secretin. 



Blood under the influ- 

 ence of secretin. Next 

 day hemoglobinuria ap- 

 pears. 



Blood under the influ- 

 ence of secretin. No 

 derangements. 



The 2"*^ rabbit got 2 cc. of the serum obtained under the influence 

 of secretin, also intravenously. A few bubbles of air, injected along 

 with the substance were responsible for a slight degree of dyspnoea 

 in the animal, which, however, disappears within a quarter of an 

 hour; 5 minutes after this intravenous injection 72 i^^g^'- of '^voratatory 

 suprarenin was administered subcutaneously. At the end of V/^ hrs. 

 the amount of sugar in the blood is 0,178 7o- After 24 hrs the 

 quantity of urine is 55 cc. with traces of sugar. 



From the experimental evidence above stated it would seem 

 permissible to conclude with a high degree of probability : 



1. that together with the blood, a substance is secreted through 

 the pancreatic vein, which, in rabbits, is capable of neutra- 



