637 
First of all experiments were made with Blastomyces rosea, a 
fairly uniform material, consisting of well isolated cells; their size 
exceeds that of anthrax spores 90 times in volume and twenty times 
in surface. The curve of survivors corresponds with type A of 
Bacillus coli, i. e. the value of & increases continuously during 
the experiment (Figs. 4 and 5). 
The same type appeared invariably also in working with a pure 
culture of press-yeast. 
Numbers of 
germs 
este. LOS. Suppose the structure of the cul- 
3-00 tures according to various degrees 
of resistance had in this case deter- 
2.00 mined the shape of the curve of 
survivors, it would not accord 
1.00 entirely with the law of fluctuating 
variability (QUÉTELET-GALTON). If it 
o did, the curves would look like those 
in Fig. 6. Intermediate between these 
and the types of the unimolecular 
reaction are the curves found for 
yeast cells. 
d. Small and large spores. 
RricHeNBacH published experiments with the spores of a small 
saprophytic bacillus. The results differed from those with anthrax 
spores. The order of dying was not in accordance with the formula 
for the unimolecular reaction, whether disinfection had taken place 
by heat or with sublimate. During the process the value of & 
increased progressively. 
As a specimen of small spores I selected those of bacillus subtilis ; 
in all my experiments the results obtained evinced a fair accordance 
with the formula of the unimolecular reactions. Only towards the 
end of the reaction / was always inclined to decrease slightly. 
This peculiarity is indeed also noticeable in my experiments with 
anthrax spores (ef. Fig. 1). It is much more conspicuous with large 
spores (see Fig. 8 and Table III). Here we had to do with spores 
of a particularly big bacillus obtained by chance from the dust settled 
in a room. Their dimensions are about twice as long as those of anthrax 
spores. Four experiments, in which the spores were disinfected by 
