742 
bi 
cations on some subsequent occasion, | found some facts which, in 
connection with the questions mentioned above, I suppose to be of 
sufficient importance to be separately communicated here. My expe- 
riments are made on cats that by a high transverse section had been 
converted into spinal-cord animals. | apply then strychnine in the 
place where a root enters, and cut besides cranically two roots. 
Consequently I make u:e of a combination of the remaining aesthesia 
method and that of the local strychnine-poisoning of the spinal cord. 
I do so to be sure, that though there may perhaps exist some doubt 
about the decidedly local application of the poison, at all events, no 
stimuli of the skin can reach the spinal cord from roots situated 
segmentzones of cats *)., of which I hope to make detailed communi- 
beside those, of which I intend to fix the skin-zone. 
By a slight touch of the skin with a pencil we look then further 
for hypevreflexion*): usually this can already be shown a few 
minutes after the poisoning. 
A peculiar fact that I have regularly stated at the determination 
and fixation of the zones, is that hyperreflexion appears first and 
strongest in a definite string-shaped zone, which however soon widens 
because cranially and caudally a strip of skin which at first was not 
hyperreflectory, becomes so now, though in an inferior degree to 
the zones that could first be indicated. When the entire strychnine- 
seementzone has reached its largest extent, this difference of intensity 
still continues to exist, so that we can distinguish a central zone 
with stronger hyperreflexion from a narrower peripheric strip with 
less strong hyperreflexion. 
This strychnine-segmentzone can consequently be divided into a 
strong hyperreflectory inner-zone which can soon be indicated, shut in 
by two feebler outer-zones appearing a little later. 
These facts show an unmistakable correspondence with those men- 
tioned above communicated partly by SHERRINGTON, partly by W. 
and v. R. I shall try to elucidate this peculiar behaviour of strych- 
nine-segmentzones in connection with what has been found by the 
above-mentioned authors, chiefly on account of indications ascertained 
with a cat (marked 32) where, under specially favourable cireum- 
stances, successively three stryclnine-segmentzones could be fixed, 
namely to the left Th. VII and Th. XI to the right The Ve 
1) Compare J. G. Dusser DE BARENNE. Die Strychninwirkung auf das Zentral- 
nervensystem. I—IV. Folia Neurobiologica. Bd. IV. V. VI. Haarlem. 1910 —1912. 
2) With this form of stryclnineapplication no Tetanus takes place, but only 
hyperreflexion. 
