768 
self declares in the meeting of the Deutsche Pathologische Gesell- 
schaft in April 1912: “Die Frage der Stellung der Granula zu den 
Tuberkelbazillen ist noch offen; aetiologisch ist die Lymphogranulo- 
matose unklar.” 
The death of a boy v. p. 5, 7 years of age, suffering from 
malignant granuloma, clinically uncomplicated with tuberculosis, 
whose autopsy took place on the 4 of June 1912, 8" 30™ post 
mortem gave us an opportunity to cultivate the “rods”, so often 
alluded to above. At the autopsy no trace whatever of tuberculosis 
was detected, only alterations pointing to malignant granuloma. 
The histologic examination of the spleen, a great number of glands, 
the bone marrow and the liver, led to the discovery of the granu- 
lation tissue which, according to STERNBERG, characterises the disease, 
whereas the typical alterations due to tuberculosis were not found. 
Nor were caviae, injected with an emulsion of the granulation tissue 
attacked by tuberculosis. 
In smears of the spleen we could demonstrate numerous rods 
fully corresponding with FRAENKEL and Mucn’s description of the 
granular rods that are found in the typical granulation tissue of the 
majority of such cases as were studied for this purpose. No other 
micro-organisms could be detected in any of the preparations. 
We have been successful in demonstrating the bacteria in only a 
few histologic preparations, as was the case with other workers on 
the subject. Whether or not this was due to the small number of 
organisms present, we are unable to say. 
In order to obtain the wished-for result, we have sown from the 
spleen on a large number of varying media and we have been 
fortunate enough to grow at once, in all the media used, a pure 
culture of a micro-organism, which proved in every respect similar 
to FRAENKEL and Mucn’s rod. 
It was especially on the blood-glycerine-potato-agar plate, used by 
Borper to cultivate the whooping-cough bacillus, that we obtained 
already after 2 > 24 hrs a strongly developed culture, which proved 
to consist of rods morphologically in no way differing from the 
granular rods. 
Before entering upon a description of our micro-organism we point 
out the fact, that we succeeded in obtaining from a jugular gland 
(patient S, twenty years old), sent to us for diagnosis, a micro-orga- 
nism similar to that obtained post mortem from the spleen of v. D. S. 
The histologic examination of this gland made us decide upon 
malignant granuloma in making the diagnosis of the typical tissue. 
Tubercular changes could not be detected in the preparations, neither 
