Malaria 97 



The tertian parasite consists of a small pale speck 

 on or in the red blood cell, exhibiting almost inces- 

 sant ameboid activity, which persists during growth 

 and the acquisition of pigment, diminishing as colour 

 increases ; its pigment granules are relatively fine and 

 are in active and constant motion ; the corpuscle in- 

 vaded by it is much enlarged and often discoloured, 

 and the hemoglobin of the former, when subjected 

 to Rornanski's stain, shows chromophile particles. 

 The spores of this form of parasite, fifteen to twenty 

 in number, are small, smooth, and round, arranged 

 irregularly, with one or more masses of pigment. Its 

 gamete is a spherical body. The cycle is twenty-four 

 hours, causing a fever that recurs every two days. 

 It occurs alike in temperate and tropical latitudes, and 

 is often encountered as a double infection, giving rise 

 to quotidian as well as tertian ague. 



The quartan parasite in its epicorpuscular and 

 unpigmented intracorpuscular life, like the tertian, 

 appears as a small rounded clear speck, its ameboid 

 movements, however, are feeble as contrasted with 

 those of the tertian, and cease entirely on becoming 

 pigmented. Its pigment is larger in amount and 

 coarser in grain, sometimes forming short rods ; its 

 spores, numbering from eight to ten, are placed 

 symmetrically around one or two massive blocks of 

 black pigment, daisy-fashion. Its gametes, like those 

 of the tertian, are spherical pigmented bodies, but 

 are smaller. It does not cause enlargement of the 

 invaded corpuscle, as does the tertian, but fills it 

 entirely when mature. It is more often found in 

 peripheral blood than are the other sorts of parasites. 

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