On Golgi's Internal Apparatus in spontaneously 

 absorbing Tumour Cells.^ 



By 

 C. Da Fano, 



Reader in Histology, King's College, University of London. 



With Plates 19 and 20. 



Introductory. 



The results obtained by the study of the Golgi apparatus of 

 growing tumours of the mouse, rat, and guinea-pig were set 

 forth in a previous paper (7) in which also the literature of the 

 subject was summarized and discussed. The apparatus was 

 found to be constantly present in the healthy cells of all 

 tumours examined, in most of which it appeared wdth certain 

 characteristic features. These were maintained through the 

 successive regrafting of the same growths even when the general 

 histological jiicture of some of them had somewhat changed 

 and the tumour cells and their apparatus had become hyper- 

 trophic or had undergone partial degeneration. 



It is now proposed to describe the behaviour of the apparatus 

 during the spontaneous absorption of some of the same tumours, 

 a point which could not be properly dealt with in the previous 

 work. Such an investigation has not, as yet, been carried out, 

 though it is important because it gives the opportunity for 

 studying the modifications of the apparatus in cells of either 

 epithelial or connective-tissue origin, undergoing regressive 

 changes after a period of active proliferation, a phenomenon 

 obtained with difficulty under different experimental conditions. 



As shown in another paper (6), spontaneously absorbing 



^ Part of the expenditure incurred for carrying out the present research 

 was defrayed by a grant from the Royal Society. The material was 

 obtained through the kindness of Dr. J. A. Murray, Director of the Labora- 

 tories of the Imperial Cancer Research Fund. 



