223, (. CLIFFORD DOBELL. 
logy of trypanosomes (T’. gambiense, etc.) has been made 
by Salvin-Moore and Breinl (70). Their results are worthy of 
special attention, because their methods were greatly superior 
to those used by the majority of trypanosome describers. So 
convinced are these two investigators of the centrosome nature 
of the blepharoplast that they call it throughout “the extra- 
nuclear controsome.” They give excellent figures of its 
origin from the ‘ centrosome,” which originally lies in the 
middle of the synkaryon. I must point out, however, that 
although the blepharoplast here appears to be the sister of 
the “intra-nuclear centrosome ”—which seems to act as a 
division centre in the “amitosis””’ these authors describe— 
there is, nevertheless, no proof that it possesses the most 
characteristic powers of a centrosome, that is, in bringing 
about nuclear division. 
‘The first observers to describe the trypanosome blepharo- 
plast as playing the part of a division centre are Franca and 
Athias (57), who have lately figured some remarkable stages 
in'T’, rotatorium. They describe irregular, amoeboid stages 
which undergo “ segmentation,” during which the flagellum 
is lost, and the blepharoplast appears to divide and function 
as a centrosome during the nuclear divisions. Although 
this fits in so well with the views which I hold, I must con- 
fess that these forms, both from the description of their 
origin and from the figures, seem to me to be abnormal or 
degenerate. 
Hartmann and Prowazek (25) have sought to bring the 
blepharoplast of Trichomonas and Trichomastix into 
line with their expanded version of Schaudinn’s ‘“‘ Doppel- 
kernigkeit” hypothesis. They base their views upon 
Prowazek’s description (78) of the forms from the lizard. 
The karyosome is regarded by them as the kinetonucleus, 
boxed up in the trophonucleus. Hence they say that “the 
basal bodies! at the root of the flagella can be interpreted as 
daughter-centrioles of the karyosome-nucleus, and hence 
correspond with the derivatives of the centrosome in the tail 
‘ What I call the blepharoplast. 
