424 



also m warmblooded uniinah? With this question Dr. L. Jendrassik 

 has occupied liimself very recently. The results obtained untill yet, 

 can be summarized in a few words, if (lie surviving heart of a 

 rabbit is perfused with a suitable salt solution, and we stimulate 

 the vagus nerve, then the liquid, leaving the stimulated heart is 

 able to accelerate in a high degree the contractions of an isolated 

 piece of gut, taken from the same animal. 



I cannot enter into these researches on this place. Dr. Jendrassik 

 will describe them in a short time in the Biochemische Zeitschrift. 

 Here we will only point out that the experiments proved, that on 

 slimnlation of the vagus nerve not only in the heart of coldblooded 

 animals but also in those of warmblooded animals substances are 

 produced, which are able to influence other organ.s in the very same 

 way, as if the vagus of those organs were stimulated by an electrical 

 current. Here the gut proved to be the most suitable object for the 

 researches. 



Further I might draw the attention of the readers to three remark- 

 able facts. In the first place it a|)peared that an extract of the 

 atrium of a rabbit's heart in sallsolution was also able to accelerate 

 the contractions of the isolated piece of gut. This experiment was 

 made in considering that it would be very probable, that the atrium 

 still contained vagus-substances, which were formed there during 

 the life of the animal. Secondly it appeared that if atropine, which, 

 as is well known, inhibits the influence of vagus-stimulation, was 

 added to the active extract, this was turned into an unactive one, 

 i.o.w. then it had no more influence on vhe movements of the gut. 

 In the third place it was found, tliat the extract of tiie ventricle- 

 muscle of the heart has a sympathetic effect on the movements of 

 the gut instead of a vagus-influence. 



The experiments on warmblooded animals described above, were 

 all performed in a room of body temperature. 



SUMMARY. 



Thus far we have been acquainted with only two forms of correlation 

 between organs, one, the eldest, established through interference of 

 the central nervous system in cases where a quick response is 

 needed (reflexesj. The second form comes into play vt^here slow 

 processes are concerned; it may be exemplified by the intluence of 

 the glandula thyroidea on metabolism and growtii. For the formation 

 of hormons the influence of the nervous sj'stem is not needed, 

 neither for the transport by the bloodcurrent. In the third neiv form 



