832 



of tiie iiervecelis and as rhaiiges of tliis apparatus in pathological 

 cases are seldom described, we tliink il justified to demonstrate them 

 in this essay, although the significance of this apparatus and its 

 changes is not at all known and has apparently nothing to do with 

 the questions we treat of in this essay. 



Wilder Pknfiei.u in his paper "Alterations of the Golgi apparatus 

 in nervecells" writes: "The Golgi apparatus presents normally in 

 the great majority of cases a complete attenuated reticulum with 

 many varicosities or lacunae. . . The strucluie is confined to the 

 cytoplasma never encroaching on (he nucleus oi' the periphery of 

 the cells. . . . The whole structure appears rarely in one half of the 

 cytoplasma only. It may be liy|)ertrophied or meagre but under 

 normal conditions the general |)atlern is sur/trisi.7i(j/i/ consUint ') for 

 each type of cells Fig. VIII shows the apparatus in nervecells of 

 normal brains. 



According to Ca.iai, the reticulum .should be more resistant to 

 pathological agents than are the neurofibrils. 





'^^:'j^ 



^ 



'^ 



■*v. 





/ 



Fig. VIII. 

 GoLGiapparatiis in normal cells. 



Penfield divides the reaction of the a|)paratus in the nervecells 

 after sectioning the nerves into three stages. 



J"^ Displacement of the unbroken apparatus to the periphery of 

 ihe cell and away from the axonehillock retispersion. 



2'"' Dissolution of the reticulum retisolutlon. 



3''^ Reconstruction. 



1) The italics are ours. 



