HS9 



nerves innerratiut/ the salivuri/ yhind make it most jird/ut/i/e tli<tt the 

 Iqssavirnx reaches the salivary plnnd along the nervous path. 



The histopathology of lijssa r'nlljl agrees mlth the e.iperiiuental 

 results tenchrnq \st that only in the second part of the incubation the 

 saliva liec.oines virulent, 27ul that the virulence of the central nervous 

 si/steut /irecedes that of the salivary gland, (expev'wnents of Bertorelli). 



As to tlie otiier side of tlie question wlieliier tlie nervous path is 

 cliosen eavlusivelg by llie \inis, we think Ihe most detailed hislo- 

 pathoiogj of the lyssa brain incompetent to solve this problem. 



REFERENCES. 



Babes. Stadiën ilber die VVutkrankheit. Vihchow's Aichiv GX 1887. 



Benedek iind Posche Ueber dif Entstehiiiig der Negrischen Körperchen. 



Benedikt. Ziir pathologische Auatomie der Lyssa. Virchow's Aichiv LXXII 1878. 



GoLui, C. Ueber die pathologisclie Histologie der Rabies experimentalis. Berl. 

 Kl. \V. 1894 N''. 14. 



Keen. Jos. Handbuch von Koli.k and Wassermakk Bd. VIII. 



KoNRADi, Daniel. Die Virulenz der Uerebiuspinalflüssigkeit beim wutkranken 

 Menschen. Zenlr. bl. f'. Neiiml uiid Psycli. 1922 Bd. 31 Referaten. 



Penfield, W. Alterations of the GoLcrapparatus in nervecells. Brain 1920, Bd. 43. 



Roux. Virus rabique dans les nerfs. Annates de I'lnstitut Pasteur II, 1888. 



San Eelice, Fr. Die Negrische KOiperchen. Zeitschrift fur Hygiene LXXIX 1915. 



ScHAFFER, K. Pathologie iind pathol. Anatomie der Lyssa. Zieqler's Beitrage 

 Bd. 7, 1890, 



ScHAFFER, K. Lyssa. Lewandowsky's Handbuch der Neurologie. 



Di Vestea e Zagari. Sulla trasniissiona delta rabbia per la via dei nervi. 

 üiorn. internaz. della scienza mediche IX. 



DESCRIPTION OE PLATES. 

 Plate 1. 



Eig. I. Negri bodies in the nervecells of the medulla oblongata. Lenz staining. 

 Eig. II. Negri bodies in the Pukkinje cells. 



Eig. 111. Negri bodies having resisted the influence of nuclease; Neurogliacells 

 having lost the greater part of their nuclei surrounding the nervecells. 

 Eig. IV. Negri bodies in slices treated with boiled nuclease. 



