III. (hnstancy of the hdcleriop/uK/ns itroperties. 



Ill our first conimmiicalion we have proved thai various haclerio- 

 phagiis strains behave differently willi regard to different typhoid 

 bacilli. 



Here follows a com|)arition of (he baclei'iophagns Sin in the sixth 

 and tenth generation with regard to four different typhoid strains; 

 the bacteriophagns was always fed with typhoid Sin. 



1. Clearing. 2. Checking. 3. Islandformation. 



vSo here we see an absolute conformity. 



The behaviour of bacteriophagus Sm with regard to strain Wi is 

 somewhat strange; in some generations we did not find any effect; 

 in some others ' as above mentioned we did find shecking of the 

 growth in broth, but no islandformation. 



We have now observed whether the properties of the bacterio- 

 phagus change when it i.s cultivated on different bacteriastrains. 



In the following tabels the results are given in which 

 I. Bacteriophagus Re direct from faeces, 

 II. ,, Re after having been fed with typhoidbacilli Sm, 



III. ,, Wi direct from faeces, 



IV. ,, Wi after having been fed with typhoidbacilli Wi, 

 V. ,, Wi after having been fed with typhoidbacilli Sm, 



VI. ,, Sm after having been fed with typhoidbacilli Sm. 



The thus obtained bacteriophage were examined with regard to 

 5 typhoidstrains. 



From this we see that the properties of the bacterioj)hagus do 

 change when another bacillus has served as food in this sense, that 

 no bacilli which used to affect are now left uninfluenced, but 

 that an increase can appear in the number of strains which are 

 influenced by the bacteriophagus; except for this strengthening 

 however the bacteriophagus retains its specific })roperties, which in 

 our opinion pleads more for a living being than for a ferment. 



