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Alcohol not only diminishes the dissociation constant of water by 
diminishing the concentration Cio in CyCon = kCy,0, but, owing 
to its ionising power being far less than that of water, it will also 
diminish the dissociation constant of a dissolved electrolyte. Therefore 
the dissociation constants of the amphoteric electrolyte urease must 
be expected to be also diminished by aleohol. 
The effects of the first influence of alcohol are, as shown in fig. 6, 
a lowering of the curve and a displacement of the maximum to the 
left; that of the second one, the diminishing of 4, and k, at the 
same rate, is evidently an increase of m, the undissociated fraction, 
without changing the abscissa of the maximum. 
Figure 8. 
Proceedings Royal Acad. Amsterdam. Vol. XXII. 
