Chemistry- — ''Infiuence of different compounds on the destruction 

 of monosacckarids by sodiurnhydroxide and on the inversion 

 of sucrose by hydrochloric acid //". By Dr. H. 1. Waterman. 

 (Communicated by Prof. J. Böeskkkn). 



(Communicated in the meeting of June 30, 1917). 



In a previous communication ') it lias been proved tliat in alkalic 

 solutions amino acetic acid and « amino propionic acid behave about 

 as one-basic acids, because they retard the destruction of glucose by 

 alkali almost as much as an equivalent quantity of hydrochloric acid. 



In acidic solution the said amino acids act about as nionacidic 

 alkali since they retard the inversion of sucrose by hydrochloric 

 acid almost in an equal degree as the equivalent quantity of strong 

 alkali. 



It could be expected that other amino-acids with a greater number 

 of atoms of carbon should in the same way show in alkalic solution 

 strong acidic, in acidic solution strong basic properties as well. 

 Experiment has confirmed this expectation. 



The following r«-aminoacids were examined : 



OH,. CH,. CH(NH,). COOH «-aminobutyric acid 



Molecular weight : 103. 



^^"s\ «-aminoisovaleric acid 



>CH.CH(NH,,.COOH ,^^l,,^, 



Molecular weight: 117. 



^^=»\ • . -J 



NCH.CH,.CH(NH,).COOH «-aminoisocaproic acid 



OH/ (leucine). 



Molecular weight: 131. 



Behaviour in alkalic solution. 



The just mentioned aminoacids prevent the destruction of glucose 

 by sodiurnhydroxide as is proved by the following. A solution of 

 50 Gr. glucose in distilled water after, being boiled was diluted 

 to 1 Liter. 



>) Chemisch Weekblad, 14, 119 (1917). These Proceedings, Vol. XX, p. 88, 

 April 27, 1917. 



