( 356 ) 
TABLE X. Table calculated from the numbers given by A. WALLER, the Negative 
variation having been taken as measure for the magnitude of stimulation. 
Fig. 10. 
R = 1.40989 +- 0.04811 Neg. var. A = 12.65056 
Bi 171,25272 
C= 41,5971165 
E 
Neg. var.| R meas. À R (calc.) E (calc.) | Menten Q 
yea | 
2.5 1.52 | + 0.01016 1.53016 
5 1.65 | + 0.00044 1. 65044 4.0573 4 — 0.0573 
70) 1.79 | — 0.01922 1.77078 9.0578 9 — 0.0578 
12 1.97 | + 0.01721 4.98721 11.9033 12 -+- 0.0967 
15 2.13 | + 0.00154 2.13154 12.3886 12.5 | + 0.1114 
19 2.32 | + 0.00398 2.32398 12.5857 12.5 | — 0.0857 | 
| | 
> 12 =0.00078722 | > 0? = 0.035729 
) middl. = 0.01493 
Q middl. =0.1091 
contraction. Whilst for the former the thresholdvalue, expressed 
in the units chosen by Water, amounts to 1,40989, for the 
muscle-stimulation it amounts to 1,5971165. From this we may con- 
clude to the important fact that this latter thresholdvalue consists 
of the total of two threshold-value’s, that therefore the threshold 
from nerve to muscle is passed only then, when the stimulus 
acting on the nerve is increased with 0,18722 of WALLER’s units. 
We may easily calculate by the aid of the formula (10) that the 
negative variation, in the moment that the magnitude of stimu- 
lation reaches the threshold from nerve to muscle, must amount to 
3,894 mM.; as Warver has stated further that each mM. of gai- 
vanometric deflection responding to the negative variation, represents 
a potential difference of 0.0001 Volt., we know that on reaching 
the threshold for the stimulation passing from the nerve upon the 
muscle, there is a potentialdifference of 0,0003894 Volt. 
I believe to have proved by the foregoing the correctness of the 
law expressing the relation between stimulus and effect. 
I wish to add the remark that I believe this law to prevail also 
for other excitable organs, especially the senses. 
I intend making further researches on this subject and communi- 
cating their results. 
(January 23, 1902). 
