178 



Horst in the Institute for Brain Researeli of Dr. AkiV;ns Kappkrs, 

 who was so kind as to lend tiieni for this evening. One sees the 

 N. Terminalis arising out of the iiemisphere, and running rostraily 

 quite independent of the olfactory lobe, as is also the case in man 

 according to Brookover fc.f. fig. 1). 



Finally I come to Amphioxus, on whose cerebral nerves I published 

 a commnnication in the meeting of the Royal Academy of October 

 the 27'''- 1894. As is known the trigeminal nerve of the craniata 

 forms a complex of two dorsal segmental nerves, the components 

 being the N. Ophthalmicus profundus (N. Nasociliaris) and the rest 

 of the N. Trigeminus. I found both these components in the two 

 nerves, of which the one appears before and the other behind the 

 first well developed myotome (which has morphologically to be 

 considered as the second). Before the homologue of the profound 

 ophthalmicus, however, there is in Amphioxus still another nerve 

 which supplies the utmost point of the snout. On account of this 

 and because it arises from the morphological fore-end of the cerebral 

 ventricle I called it the N. Apicis. 



At fii'St 1 thought that the N. Apicis would be aborted in the 

 higher chordata, but shortly before the publication of my article the 

 preliminary communication of Pinkus appeared (Anat. Anz. 1894), 

 in which he reported the discovery of a new nerve in Protopterus, 

 later named the N. Terminalis by Locy. 



This had to be considered the homologue of the N. Apicis consi- 

 dering its course, ramification and origin, not from the infundibulum 

 as I concluded out of the preliminary commnnication, but near the 

 Lamina Terminalis as became clear when the more extensive treatise 

 appeared the next year. 



I must acknowledge that I have later on sometimes doubted 

 whether this homologisation were correct, when I read the investi- 

 gations of Locy in the Selachii, of Brookovkr and Shkldon in the 

 Ganoids and Teleostei, and of Ernst de Vries and Döllken in the 

 mammals, because all these wi'iters assert that the peripheral ter- 

 mination of the N. Terminalis is wholly' or principally limited to 

 the olfactory mucous membrane (or in mammals to the vomeronasal 

 organ, which is covered by a split-off part of the olfactory mucous 

 membrane). In Amphioxus on the other hand the N. Apicis stands 

 in no relation whatever to the covering of the olfactory groove. 



After however reading the research of Huber and Guild (1913) 

 this doubt was dispelled. 



Their illustration (c. f. fig. 2) shows the N. Apicis of Amphioxus 

 in the rabbit — I could almost say "in optima forma", even to the 



