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disaeininated ganglionic cells, wliicli have already been lonj? known 

 in the N. Apicis. 



As the N. Apicis is an ordinary cutaneous nerve '), the relation 

 in which the N. Terminalis stands to the olfactory epithelium in 

 some of the higher animals must be of a secondary nature. It is 

 even possible that the terminal i-amitication of the nerve has become 

 principally limited to the olfactory mucous membrane, as appears 

 to be the case in many fishes. 



Thus has the N. Terminalis completed its course through science 

 in 20 years (L894 — 1914) beginning in the lung-fishes, I may as well add 

 in Amphioxus, and ending in man. It can no longer be doubted that 

 we have here to do with an independent cerebral nerve and not 

 with a bundle of the olfactory nerve. In most or all of the craniata 

 however branches of both nerves run close alongside of each other, 

 and on account of this it is difticidt to distinguish their peripheral 

 distribution. 



From Amphioxus to man the N. Terminalis is provided with 

 disseminated ganglionic cells, which can partly be gathered together 

 to one or more ganglia. On the other hand the olfactory nerve 

 (including its specialised bundl-e, the N. Vomeronasalis of the Amniota) 

 is distinguished by the complete absence of ganglionic cells. 



At the end of this summary I want here to express my thanks 

 to Di'. Akiëns Kappers, who was so kind as to send me for perusal 

 a dozen treatises on the N. Termijialis, neai'ly all of American 

 investigators, which have become the occasion of this address. 



POST SCRIPTUM. 



Early in March Dr. Kappers sent me for perusal a copy of a 

 new work by Brookover, which he had received a few days earlier: 

 "The Peripheral Distribution of the Nervus Terminalis in an Infant" 

 (Journal of Comp. Neurology Vol. 28 N". 2). 



Brookover found the branching of the N. Terminalis in the nasal 

 septum of the child analogous to that in the rabbit, according to 

 HuBER and Guild, only much more strongly developed. In it he 

 could count about 1500 ganglionic cells, not considering the Ganglion 



1) It is a well known fact that ganglionic cells are found not only in the first 

 but also in the secomi cutaneous nerve (N. Ophlhalmicus prof.) of Amphioxus. 

 De Quathefages discovered them here in 1845 already, but held them for mucous 

 cryptes, "cryptes mucipares". Incorrectly it is assumed that peripheral ganglionic 

 cells are not present in the other nerves. I found multitudes of them in the nerves 

 running under the atrial epithelium wliich covers the intestine and the liver. 



12* 



