550 



0,1 cciii. urine from the left kidney needs 0,88 ccm. Iodine solution which 



0,88—0,12 „ , 



corresponds to = 0,19% glucose. 



4 



Retained l)y the right kidney 0,21—0,1875 = 0,02250/,,. 

 Retained by the left kidney 0,21—0,19 = 0,02%. 



These quantities are so small that one may say that practically 

 all the laeviilose is allowed to pass by the glomerulus epithelium. 

 The following experiments affirm this i-esult. 



Experiment 2 (July 12). 

 The same solution as used in experiment 1. 

 Reduction (0,1 c.c.) urine of right kidney 0,2125%. 

 Reduction (0,1 c.c.) urine of left kidney 0,215'Vo- 

 Retained by right kidney 0,21—0,2125 = 0. 

 Retained by left kidney 0,21-0,215 = 0. 



Result: iVo laevulose retained by the glomerulus epithelium. 



Experiment 3 (July 18). 



Experiments 1 and 2 were repeated with fresh solution. 

 Reduction 0.1 c.c. of solution passed 0,18 '/q. 

 Reduction 0,1 c.c. urine of right kidney 0,18%. 

 Reduction 0,1 c.c. urine of left kidney 0,18"/o, 



Result: Xo laevulose retained. 



Experiment 4 (July 14). 

 The same solution passed as in experiment 3. 

 Reduction 0,1 c.c. urine of right kidney 0,1825%. 

 Reduction 0,1 c.c. urine of left kidney 0,1825" q. 



Result : No laevulose retained. 



It has probably not escaped attention that the laevulose solution 

 used above causes about twice as strong a reduction as a glucose 

 solution of 0.17, viz. 0.1 87o on an avei-age. Whei-e it could be possible 

 that a solution with a so much larger reductive capability could. 

 just in connection with that fact, be allowed to pass by the glome- 

 rulus epithelium, we experimented with a solution in which there 

 was 0.057„ laevulose instead of O.V/^. 



Experiment 5 (July 15). 



Ringer's solution in which 0,05% laevulose has been dissolved. 



Reduction 0,1 c.c. of perfusion liquid 0,095%,. 



0,1 c.c. urine of right kidney: 0,5 c.c. Iodine solution; reduction 0,095%. 



0,1 c.c. urine of left kidney: 0,52 c.c. Iodine solution; reduction 0,1%,. 



0,1 cc. urine of right kidney: 0,52 c.c. Iodine solution; reduction 0,1%. 



detained by right kidney 0,095-0,095 = 0. 



Retained by left kidney 0,095—0,1 = 0. 



Retained by right kidney 0,095—0,1 = 0. 



