556 



does not, like hievulose, pass tkrough the kidney altogether, but is 

 generally retained to a slight degree. 



This indicates in any case that galactose is used in tlie body. We 

 know in<ieed that lactose is buill up from dextrose and galactose 

 and an article of Else Hirschbekg ') from Winthrstkin's laboratory has 

 just appeared in which a certain affinity, that is wanting in laeviilose, 

 becomes clear between glucose and galactose in connection with the 

 spinal cord. 



We repeat, that tiie amount of galactose retained is in all the 

 experiments expressed in the percentage of glucose. This is also the 

 case with other sugars. 



D. MaDnose. 

 Experiment 25 (Aug. 20). 



In the suitable perfusion liquid consisting of NaCl 0,5"/,,, NaHGOg 0,2857o. 

 KGl 0,01% and GaCli 0,02"o, 0,1 'Vo mannose is dissolved. 



0.1 c.c. perfusion liquid : 0,45 c.c. iodine sohilion ; reduction 0,0825%. 

 0,1 c.c. urine of right kidney : 0,48 c.c. Iodine solution ; reduction 0,097o' 

 0,1 c.c. urine of left kidney : 0.46 c.c. iodine solution ; reduction 0,085%. 

 Retained by right kidney : 0,0825—0,09 ^ 0. 

 Retained by left kidney: 0,0825—0,085 = 0. 



Experiment 26 (Aug 20). 



The same perfusion liquid as in exp. '2'». 



0,1 c.c. urine of right kidney : 0,45 c.c. iodine solution ; reduction 0,ü8257o- 



0,1 c.c. urine of left kidney : 0,44 c.c. Iodine solution ; reduction 0,08'V(). 



Retained by right kidney: 0,0825—0,0825 = 0. 



Retained by left kidney : 0,0825—0.08 ^ 0,0025» „. 



Thus also in this experiment no mannose was retained. 



Experiment 27 (Aug. 21). 



0,1 c.c. perfusion liquid: 0,35 c.c. Iodine solution: reduction 0.0575"'o- 



0,1 c.c. urine of right kidney: 0,37 c.c. Iodine solution; reduction 0.0625%,. 



0.1 c.c. urine of left kidney: 0.35 c c. Iodine solution; reduction 0,0575%,. 



0,1 c c. urine of right kidney: 0,35 c c. Iodine solution; reduction 0,0575%. 



In this exp. also no inannose is retained. 



Experiment 28 (Aug. 21). 



The same perfusion liquid as in exp. "11. 



0,1 c.c. urine of right kidney- 0,36 c.c. Iodine solution; reduction 0,06%,. 



0,1 c.c. urine of left kidney: 0,36 c.c. Iodine solution; reduction 0,06"/o- 



Retained by each kidney 0,0575—0,06 = 0. 



In this experiment the Kidneys have also passed all the mannose. 

 From these experiments we may draw the conclusion that the 

 glomerulus epithelium is totally permeable to inannose. 



We shall now report some experiments made with mutually 

 isomeric disa cc har ides : saccharose, maltose and lactose. 

 1) Else Hirschbekg: Zeitschr. f. physiol. Chemie, 100, (1918). 



