557 



These experiments seemed of importance because, amongst other 

 reasons, their molecules are hxrger than those of the monosaccharides 

 already considered. If the permeability was in connection with this 

 size it would probably appear that the glomerulus epithelium was 

 impermeable to the dissacharides. 



E. Saccharose. 



To estimate the quantity of saccharose in the perfusion liquid 

 and in the urine, 0.1 cc. of the liquid was heated to 37° C. during 

 17, hours with 0.15 cc. hydrochloric acid 1 : 1 and the reduction 

 of the solution thus obtained determined. 



Experiment 29 (July 17). 



The perfusion liquid contains 0,1% cane sugar. 



After inversion it causes a reduction of 0,12757ü- 



0,1 cc. urine of right kidney after inversion causes 0,13"/,, reduction. 



0,1 cc. urine of left kidney after inversion causes 0,13257„ reduction. 



Retained by right kidney; 0,1275-0 13 = 0. 



Retained by left kidney: 0.1275—0,1325 = 0. 



Result: all the cane sugar has passed through. 



Experiment 30 (July 17). 



The same perfusion liquid as in exp. 29. 



Reduction 0,1 cc. urine of right kidney after inversion 0,11257o- 



Reduction 0,1 e.c urine of left kidney after inversion 0,095%. 



Retained by right, kidney : 0,2275-0,1125 = 0,015",o. 



Retained by left kidney: 0,1275-0.095 = 0,032'Vo- 

 Here follows a table in which seveial experiments are summarised. 



There can be no doubt that the glomerulus epithelium has retained 

 saccharose, either as such or in the form of glucose which has then 

 been formed through the splitting of saccharose in the glomerulus 

 epithelium, while the laevulose has passed into the urine. This latter 

 alternative is of no great probability. 



F. Maltose. 



Experiment 35 (July 16). 



In the suitable perfusion liquid with 0,285%, NaHCO^, 0,15"/o maltose is dissolved. 



0,1 cc. perfusion liquid : reduction 0,0825"/o- 



0,1 cc. urine of right kidney: reduction 0,07%,. 



0,1 cc. urine of left kidney: reduction 0,07 Vo- 



Retained by each kidney: 0,0825—0.07 = 0,0125 '/„. thus hardly any at all. 



Experiment 36 (July 16). 



The same perfusion liquid as in exp. 35. 



0,1 cc urine of right kidney: reduction 0,0875%,. 



0,1 cc urine of left kidney : reduction 0,0625%. 



Retained by right kidney: 0,0825—0,0675 = 0,015%. 



Retained by left kidney : 0,0825-0,0625 = 0,02 Vo- 



