559 



this dissacchavide is built up from tioo molecules of glucose, and that 

 the glomerulus epithelium is permeable to glucose to a vert/ slight degree. 



G. Lactose and a mixture of glucose and lactose. 



Experiment 41 (July 3). 



0,20/i) Lactose is dissolved in the perfusion liquid. 



0,1 c.c. of perfusion liquid: reduction 0,14"/o. 



0,1 c.c. urine of right kidney: reduction 0, 1375°/o. 



0,1 c.c. urine of left kidney : reduction O.lé^/o. 



Retained by right kidney: 0,14—0,1375 = 0,0025%. 



Retained by left kidney : 0,14—0,14 = 0. 



Experiment 42 (July 3). 



0,1 c.c perfusion liquid: reduction 0,11^'/,,. 



0,1 c.c. urine of right kidney: reduction O,!!"/^. 



0,1 c.c. urine of left kidney: reduction 0,1075%. 



Retained by right kidney: 0,11— 0.11 n^ 0. 



Retained by left kidney: 0,11—0,1075=0,0025%. 



Here again tlie kidney has i-etaiiied no, or very little, lactose. 



Experiment 43 (July 3). 



The same perfusion liquid as in exp. 42. 



0,1 c.c. urine of right kidney : reduction O,1O750/q. 



0,1 c.c. urine of left kidney: reduction 0,1075'^/o. 



Retained by each kidney: 0,11—0,1075 = 0,0025%. 



Here again neither of the kidneys retained lactose. 



Experiment 44 (Juli 4). 



0.1 c.c. perfusion liquid: reduction 0,14%. 



0,1 c.c. urine of right kidney: reduction 0.1450%. 



0,1 c.c. urine of left kidney: reduction 0,13257o- 



Retained by right kidney: 0,14 — 0,1450 = 0. 



Retained by 'eft kidney: 0,14—0,1325 = 0,0075%. 



Lactose has thus been retained by neither of the kidneys. 



From this we may draw the conclusion that the glomerulus 

 epithelium allows the lactose to pass altogether, although it is built 

 up from glucose and galactose, of which compounds the former is 

 retained to a large degree, and galactose as well, although less. 



From a theoretical as well as from a clinical point of view it 

 seemed of importance to investigate how the kidney would behave 

 towards a mixture of lactose and glucose. 



From these e.vperiments we learn that the retention of glucose by 

 the kidney is not influenced by lactose. The latter is passed while 

 glucose is retained to the same degree as when there was no lactose 

 present. 



This result is in accordance with the use which for a 



