and 



( 254 ) 



Ay will be seen A is situated in the cardea region. 



B in the border region between cardea 



fundus part 

 C in the fundus region 

 D in the border region between fundus and 



pylorus part 

 E in the pylorus region 

 F on the duodenum near to pylorus. 



With respect to this figure we must point out that for all our 

 experiments with gastric mucous membrane, the letters have the same 

 meaning. 



In the experiment of which (able I gives the results, the agar 

 columns of 3 cc. remained during 14 1 /, hours on the mucous mem- 

 brane. Then the agar was cut line and mixed with 3 cc 0.4 % HO 

 and each of the mixtures thus obtained was made to exert its digestive 

 influence on two tubes of albumen. 



The four numbers which in the following table are connected by 

 + represent the lengths of the four albumen columns, digested at 

 the 4 sides of the two tubes. 



TABLE I. 



Digested after 12' ' 3 lirs. 



From this table is seen : 



1. That in the cardia region {A and A') the, amount of pepsin is 

 small, increases towards the fundus (B and B'), reaches its climax 

 there (C and C') and decreases towards the pylorus (D and D'). 

 In the duodenum we also meet with pepsin, but its quantity is small. 



2. The table shows that in both halves of the stomach the quantity 

 of pepsin was equal in corresponding parts. 



If we speak here of pepsin we mean pepsin and pepsinogen. As 

 has been said before and will further be demonstrated pepsinogen 



