206 ROBERT K. S. I-IM 



species, and to determine the general relationship which exists 

 between the mucoid group and the peptic cells of the fundus. 

 The technique employed is similar to that referred to in Part I. 

 The material was invariably obtained from the newly-killed 

 or from the living anaesthetized anijnal. Human material 

 came partly from the operation table, partly from the post- 

 mortem. Acid formol fixation and Mallory's and Heidenliain's 

 methods of staining were the routine procedures. 



The Mucoid Cells of the Fundus. 



Human. — In man mucoid cells are abundantly present. 

 Thej'^ have the same characteristics as those of the cat except 

 that their cytoplasm is more homogeneous and stains a lighter 

 blue with Mallory. Their distribution is somewhat different ; 

 they form the entire central lining of rather less than the super- 

 ficial two-thirds of the secreting tubule — hence their regular 

 cubical outline. This portion of the tubule is thinner than the 

 deeper portion which (with rare exceptions) contains typical 

 ])eptic and oxyntic cells. A few tubules are lined throughout 

 their whole extent by mucoid cells. There is not the same 

 amount of intermingling between the mucoid and peptic cells 

 as in the cat, and thus the mucoid portion of the tubule is more 

 easily defined, especially since it is narrower than the peptic 

 portion. 



Dog. — The mucoid cells of the dog are intermediate in 

 appearance between those of man and the cat. In some 

 individuals the cytoplasm is almost homogeneous and stains 

 lightly with ]\Iallory ; in others it is more reticular and stains 

 heavily as in the cat. This may be due to functional changes. 

 The distribution of the cells, however, shows fewer mucoid cells 

 in each tubule, i.e. they line less than the superficial half; nor 

 do the mucoid and peptic cells intermingle to any great extent. 

 The widening of the calibre of the deep portion of the tubule 

 occurs gradually as in the cat, but nevertheless the mucoid 

 and peptic portions are sharply marked off from each other. 



Eabbit. — The mucoid cells of the rabbit stain faintly 

 blue with Mallory and are nearly homogeneous ; they appear 

 like those of man. They are not easily made out since they are 



