THE GASTRIC MUCOSA 209 



(along the lesser curvature) for only a very short distance 

 (about 3 mm.). The acmi are mainly serous, a few being 

 mucous ; the cells lining the terminal ducts have granules 

 in striae and have centrally-placed nuclei. True mucoid and 

 peptic elements are present beyond the cardiac area described 

 above, the former forming a boundary zone of about 3-4 mm, 

 with the oyxntic cells before the latter are met with. 



The pyloric region is somewhat larger than that of the cat, 

 since oxyntic cells are only seen about 35-40 mm. from the 

 duodenum (see table, p. 207). There is almost no boundary 

 zone ; the peptic cells appearing a few millimetres beyond the 

 oxyntic. The gland-cells are more mucoid than those of the 

 cardia, but like these show a well-marked non-mucoid basal 

 area. 



Langley (5) described the cells of the rabbit's fundus along 

 the greater curvature as being finely granular and similar in 

 appearance to the pyloric cells, while the cells of the remainder 

 of the fundus are coarsely granular. I have not been able 

 to make out this distinction, but perhaps Langley took the 

 superficial mucoid cells to be the only kind of central cell 

 and failed to see the peptic (coarsely granular) cells in the 

 deepest part of the mucous membrane. 



Frog. — There are no true cardiac glands in the frog ; the 

 peptic cells merely stop short at the end of the oesophagus 

 while mucoid and oxyntic cells make their appearance. The 

 pyloric region extends about 3-4 mm. from the duodenum ; 

 its gland-cells are not different from the mucoid cells of the 

 fundus. 



General Conclusions. 



The results of this investigation confirm those of Bensley (1) 

 and more especially those of Cade (2), who has examined all 

 the species dealt with here. They show that the fundic 

 mucoid cells vary slightly in appearance in different animals, 

 and that their distribution in the tubule is roughly about the 

 superficial half. From the study of new-born cats it is found 

 that the peptic cell arises from cells of the mucoid type. This 



