572 F. A. E. CEEW AND HONOR B. FELL 



appear that they are colloid globules of the same nature as those 

 described in the goat and the rabbit. A coloured drawing has 

 been made (PI. 18, fig. 5) from one of the more typical of 

 these. The figure^ was taken from a section stained with 

 Mallory's stain. The body is seen to consist of a darker central 

 area surrounded by a lighter ring. It is invested by a proto- 

 plasmic syncitium. The tubule is lined with epithelial cells 

 most of which are attached to the basement membrane. 



The formation of the colloid body seems to be initiated by 

 the nucleolus of one of the more centrally situated nuclei. 

 The process appears to be as follows : The nucleolus increases 

 to several times its original size, apparently absorbing the 

 rest of the nuclear material. The nucleus becomes more and 

 more vacuolated and is finally reduced to a large clear vesicle 

 containing an enormous nucleolus. All stages intermediate 

 between a normal nucleolus in a reticulated nucleus and a well- 

 developed colloid globule are seen (PI. 18, fig, 2). 



Intertubular Tissue (PI. 22, fig. 21)— The Inter- 

 stitial Cells show reduction instead of hyperplasia. They 

 occur in columns and groups which are usually closely applied 

 to the basement membrane of the tubule. 



A large elongate group is found intercalated between two 

 layers of the tunica albuginea. The nuclei are spherical and 

 have a very distinct nucleolus. T'hey are usually eccentrically 

 situated. The cytoplasm is very vacuolated, especially in those 

 cells which occur in the tunica albuginea. In many of the 

 latter the cell is almost an empty vesicle. Fibrous tissue is 

 present in small quantities. 



Epididymis . — The epididymis appears normal and typical. 

 It is lined with the usual columnar ciliated epithelium resting 

 on a basal layer. The lumen in places contains masses of 

 debris. The connective-tissue stroma is normal. 



Vasa Efferentia. — These consist of the usual layer of 

 columnar ciliated cells somewhat shallower than that of the 

 epididymis. 



Tunica a 1 b u g i n e a . — The tunica albuginea is typical and 

 normal. 



