OVUM-LIKE BODIES IN THE TESTIS 577 



Fig. 5. — Cat. yeminiferous tubule, x 470. Stained Mallory. The 

 centre of the lumen is filled by structureless protoplasm in which is seen 

 a spherical body brilliantly stained with Orange G, The peripheral cells, 

 though showing no mitosis, are comparatively normal. 



Fig. 6. — Goat. Ovum-like body within a seminiferous tubule, x 470. 

 Stained Mallory. The peripheral parts stain blue indicatmg commencing 

 calcification. The germinal epithelium is more degenerate than in fig. 7. 



Plate 19. 



Fig. 7. — Goat. Seminiferous tubule containing two of the ovum-like 

 bodies, x 320. Each body is composed of concentric layers sharply 

 demarcated and apparently homogeneous. The central area is paler and 

 the investing cells are very degenerate. The cytoplasm of the germinal 

 epithelium shows no cell-limits. 



Fig. 8. — Goat. Seminiferous tubule, x 200. The mass of cell detritus 

 within the tubule is undergoing a colloid degeneration. Globules of 

 colloid are seen at the top right-hand part of the mass. 



Fig. 9. — Goat. Seminiferous tubules, x 125. In the upper right-hand 

 corner is a tubule containing an aggregation of cellular material showing 

 a further stage of colloid degeneration than in fig. 8. A single ovoid body is 

 also seen withm a very degenerate tubule. In this there are no concentric 

 layers, but the mass contauis a number of highly refractile granules. 



Fig. 10.— Goat. Seminiferous tubule. x 320. The tubule is less 

 degenerate than the preceding. Only the peripheral layer of epithelial 

 cells is present. In the centre of the lumen is an aggregation of cells 

 surrounding a circular body built up of two concentric rings and a darker 

 central area. The investmg cells show two distmct layers, an outer in which 

 the nuclei are visible and an iimer in which no cellular structure can be 

 distmguished. 



Plate 20. 



Fig. 11. — Rabbit. Semmiferous tubule, x 400. The peripheral cells 

 (spermatogonia) are still comparatively normal. Two examples of pluri- 

 polar mitosis are seen in the bottom right-hand corner of the lumen. The 

 centre of the tubule is filled with a loose syncitium m which lie a few large 

 clear spermatocytes and some degenerate nuclei. 



Fig. 12. — Rabbit. Seminiferous tubule, x 770. The centre of the tubule 

 is occupied by a hypertrophied nucleus surrounded by a stellate mass of 

 protoplasm. This probably represents the first stage in the formation 

 of these intra tubular bodies. 



Fig. 13. Rabbit. Seminiferous tubule. x285. Showing the thick 

 fibrous layer surroimding the tubules. This is apparently formed by the 

 cells of the basement membrane m response to stimulation by the colloid, 

 some of which probably percolates through the peripheral epithelial cells. 



Fig. 14 • — Human. Seminiferous tubules, x 285. Shows the enormou 



