( J5 ) 



granulans externa and the complication of the lamina granulans 

 interna (Brodmants), which latter is doubled by the line of Vicq 

 d'Azir (in WEiGEET-preparations) ; between the two sub-divisions of 

 the inner granular layer tiie isolated polygonal cells (stellate) cells 

 are found. The fifth layer (lamina ganglionaris) contains' well- 

 developed pyramidal cells, lamina VI consists of cells of a multiform 

 type. 



Figure 2 is a ]»hotogram of a section in the homologous level in 

 the brain of the operated cat, taken from the gyr splenialis. The 

 lamina zonalis and pyramidalis (I and III) do not show any marked 

 loss of cells. Nevertheless in these, and probably in the granules of 

 the inner granular layer, several elements are more or less abnormal. 



Compared with the normal, too many glia cells are to be found 

 between and around the nerve cells. The latter moreover show for 

 the greater part an abnormal situation of the nucleus; the toluidine 

 staining is frequently not of the Nissltype, but several cells are 

 coloured rather diffusely darkblue. The impression made by the 

 deeper part of the supragranular pyramidal cells is that of a recovery 

 from a functional alteration. 



The number of stellate cells within the IV (inner granular) layer 

 has not decreased ; many of them are not coloured with the same 

 distinctness as in normal preparations ; satellite-glia elements, up to 6 

 or 8, are often situated immediately on their surface. 



The lamina ganglionaris (V) shows the most marked alteration. 

 In normal preparations of this region, well-developed large pyramidal 

 cells are present in this layer, not in very great number it is true, 

 and not in a quite continuous row ; particularly in the gyr. ento- 

 lateralis the series show^s small gaps. On the contrary these large, 

 well-stained cells are for a good deal lacking in most of the homo- 

 logous sections of the operated cat. Nevertheless a reservation must 

 be made for few subgranular pyramidal cells, which are seemingly 

 wholly unaltered. The preparations of the left hemisphere, taken 

 from the most caudal part of the area striata present in exactly the 

 same way the above-described lack of deep pyramidal cells. These 

 sections being stained after van Gieson show, moreover, a marked 

 loss of fine nevve fibres up to, and including, the inner granular 

 layer, which is not to be found in Wkigekt preparations. The fact 

 that the left area striata was primarily injured in its frontal third 

 renders it difficult to give an unequivocal interpretation to the dege 

 ne ration of the sheath less fibres. 



In the multiform cell layer it is impossible to demonstrate a 

 veritable lack of nerve-elements. On the other hand, secondary alter- 



