( 16 ) 



ations are very evident; many cells show anomalous form and 

 colouring ; the position of the cell-nucleus — though in these smaller 

 elements not easily to be judged — is very often excentric. Glia cells 

 in the different stadia of activity and inaction ^) are present in great 

 number, particularly surrounding the nervous elements, in contrast 

 to their behaviour in the fourth (and third) layer, where they are 

 mostly scattered betireen the nerve cells. 



Figure 3 represents a section through the cortex of the gyr. ecto- 

 lateralis of a normal cat on the spot marked in diagram \a. The 

 lamination is otherwise than in the area striata. Six layers are to 

 be easily recognised. Lamina II and III are larger than in the layer 

 between lam. zonalis and lam. granulans interna in the visuo-sen- 

 sory zone. In the deepest part of lamina III a row of larger pyra- 

 midal cells is visible immediately above the inner granular layer. 

 In the fifth layer the pyramidal cells are of a somewhat smaller 

 size than those in the area striata, but more numerous. The lamina 

 multiformis (VI) is well developed, and contains fusiform and angular 



cells -). 



The homologous sections of the right hemisi)here of the operated 

 cat present in the S'*^, 4''\ and (i^'' layers about the alterations as 

 mentioned before in the gyr-splenalis. The principal anomalies are 

 shown by the lamina ganglionaris (V). Photogram 4 represents this 

 layer (normal) more highly magnified; it is easy to identify in this 

 figure several of the cells of fig. 3. The infragranular pyramidal cells 

 are visible in au almost diagonal line from left to right. 



In an almost similar way these elements are situated in figure 5, 

 taken from a corresponding section through the operated brain. It 

 is evident that the cells mentioned in the latter have decreased in 

 number; the few that are visible are of a well-known, abnormal 

 type with regard to their dark blue colour, the absence of a distinct 

 nucleus and the nodosity of their surfaces. The supragranular pyra- 

 midal cells on the same photo form a pregnant contrast to the 

 infragranular ones, as they have on the whole quite a normal appearance. 

 The non-pyramidal infragranular cells in the fifth layer are doubt- 

 lessly less numerous than they should be; histological alterations 

 cannot be demonstrated with sufficient certainty. The nerve cells 

 of the lamina multiformis VI lie apparently closer together than in 

 the noi-mal preparations; their protoplasm has mostly been stained 



1) See: E. de Vries: Exper. Untersuch. Ü. die Rolle der Neurol, etc. Arbeiten 

 aus V. MoNAKOw's Institut 1909. 



2) More frontally, in the transverse level of the splen. corp. callosi, many of the 

 infragranular pyramidal cells in the gyr. ectolat. are of an uncommonly large size. 



