792 
at the hygienic laboratory at Utrecht. Their body-weights were 
widely different and did not change much with the same individual. 
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Liters of air 
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The lowest temperature, at which we worked was 3°, the 
highest 30°. 
The experiments were made in May, June, July, September, 
October, November 1911 and in January, February, and July 1912. 
There was only a small difference in the summer- and the winter- 
attire. No overcoat was ever put on in cold weather nor was 
any article of attire taken off in the summer. As serious errors 
would originate in case the subject should shiver, this was a point 
of careful observation. 
In Jooking over our results, in the first place with regard to the 
amount of oxygen, we notice rather considerable fluctuations with 
the same subject under apparently similar circumstances, which is 
in accordance with the experience of other workers. 
Benepict'), for instance, found in experiments with the same 
subject under equal circumstances the following oxygen-consumption : 
194—213—169, showing as great a difference as 26°/,. 
We also found with N. on 15—7—’12, at 30°, 765,5 mm. baro- 
metric pressure, relative moisture of 52°/,, the value 256,8, and on 
16—7--'12, at 30° and 765,5 mm. barometric pressure, relative 
moisture of 50°/,, the value 292. This yields a difference of rather 
more than 13°/,. 
It is obvious, therefore, that if we wish to demonstrate seasonal 
influence, an extended series of experiments is required, and further- 
more, that only striking differences should be attended to. If we 
take the average of the results at a temperature below 13° (the 
months of Nov. Dec. Jan. Feb.) and of those above 18° (the other 
months) we note: 
1) Benepicr. The metabolism and energy transformation of healthy man during 
rest. (Carnegie Institution of Washington. Publication no, 126, 1910, p. 107.) 
