( 602 ) 

 CH 3 — NH 



To this I may add the CH, C< ) recently investigated with Dr. 



CO— NH 

 hydro-uracil 



(i? lady lured) 

 Friedmann, which yields, equally readily, a mononitroderivative 1 ), 

 which on boiling with water yields, in an analogous manner, carbon 

 dioxide and finitraminopropionamide, from which we have prepared 

 p nitr amino propionic acid, also its barium and silver salt. 



This decomposition proves the position of the nitrogroup, and at 

 the same time these substances are all a confirmation of the first rule 

 because the group NH, which is placed between the two CO-groups, 

 has not taken part in the reaction. 



CH, 

 CH,- CH, | \ 



II I \ 



CH, CO and CH, CO 



I I I I 



CH,— NH CH 3 .CH— NH 



« Piperidone a methylpyrrolidone 



gave with nitric acid N,0, presumably derived from a nitro-compound 

 unstable towards nitric acid at the ordinary temperature ; for it has 

 been shown that some nitramides are decomposed by nitric acid at 

 the ordinary temperature with evolution of nitrous oxide; whilst 

 others may be evaporated with this acid 011 a boiling waterbath 

 with impunity. 



The rule was confirmed five years ago with cycles in which 

 oxygen takes part, for instance 



CH 2 O-CH, 



[i. céto tetrahydro-oxazole. ,u. céto pentoxazolidine 



gave on evaporation with nitric acid, mononitroderivatives, which on 



T ) Tafel stated about this substance (Ber. d. D. ch. G. 33 p. 3385) that it is 

 not affected even by prolonged boiling with concentrated nitric acid; evidently he 

 has not used absolute nitric acid. 



